AIMC Topic: Psychotic Disorders

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Accuracy of machine learning methods in predicting prognosis of patients with psychotic spectrum disorders: a systematic review.

BMJ open
OBJECTIVES: We aimed to examine the predictive accuracy of functioning, relapse or remission among patients with psychotic disorders, using machine learning methods. We also identified specific features that were associated with these clinical outcom...

Exploring Potential Medications for Alzheimer's Disease with Psychosis by Integrating Drug Target Information into Deep Learning Models: A Data-Driven Approach.

International journal of molecular sciences
Approximately 50% of Alzheimer's disease (AD) patients develop psychotic symptoms, leading to a subtype known as psychosis in AD (AD + P), which is associated with accelerated cognitive decline compared to AD without psychosis. Currently, no FDA-appr...

Preliminary investigation of an artificial intelligence-based cognitive behavioral therapy training tool.

Psychotherapy (Chicago, Ill.)
We developed an asynchronous online cognitive behavioral therapy (CBT) training tool that provides artificial intelligence- (AI-) enabled feedback to learners across eight CBT skills. We sought to evaluate the technical reliability and to ascertain h...

Uncovering key predictive channels and clinical variables in the gamma band auditory steady-state response in early-stage psychosis: a longitudinal study.

Acta neuropsychiatrica
OBJECTIVE: Psychotic disorders are characterised by abnormalities in the synchronisation of neuronal responses. A 40 Hz gamma band deficit during auditory steady-state response (ASSR) measured by electroencephalogram (EEG) is a robust observation in ...

AI-based medication adherence prediction in patients with schizophrenia and attenuated psychotic disorders.

Schizophrenia research
OBJECTIVE: The capacity of machine-learning algorithms to predict medication adherence was assessed using data from AiCure, a computer vision-assisted smartphone application, which records the medication ingestion event.

RNA Editing Signatures Powered by Artificial Intelligence: A New Frontier in Differentiating Schizophrenia, Bipolar, and Schizoaffective Disorders.

International journal of molecular sciences
Mental health disorders are devastating illnesses, often misdiagnosed due to overlapping clinical symptoms. Among these conditions, bipolar disorder, schizophrenia, and schizoaffective disorder are particularly difficult to distinguish, as they share...

Evolution of Linguistic Markers of Agency, Centrality and Content During Metacognitive Therapy for Psychosis: A Pilot Exploratory Study.

Early intervention in psychiatry
AIM: Metacognitive Reflection and Insight Therapy (MERIT) is a form of person-centred psychotherapy that promotes recovery-oriented outcomes by targeting metacognitive capacity. Previous research has shown the feasibility and clinical benefits of MER...

Classification of psychosis spectrum disorders using graph convolutional networks with structurally constrained functional connectomes.

Neural networks : the official journal of the International Neural Network Society
This article considers the problem of classifying individuals in a dataset of diverse psychosis spectrum conditions, including persons with subsyndromal psychotic-like experiences (PLEs) and healthy controls. This task is more challenging than the tr...

Automated linguistic analysis in youth at clinical high risk for psychosis.

Schizophrenia research
Identifying individuals at clinical high risk for psychosis (CHRP) is crucial for preventing psychosis and improving the prognosis for schizophrenia. Individuals at CHR-P may exhibit mild forms of formal thought disorder (FTD), making it possible to ...

Cognitive profiles across the psychosis continuum.

Psychiatry research
Cognitive impairments are core features in individuals across the psychosis continuum and predict functional outcomes. Nevertheless, substantial variability in cognitive functioning within diagnostic groups, along with considerable overlap with healt...