PURPOSE: Few features characterizing the dosimetric properties of the patients are included in currently available dose-volume histogram (DVH) prediction models, making it intractable to build a correlative relationship between the input and output p...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 31, 2018
BACKGROUND AND PURPOSE: Intensity-modulated radiation therapy (IMRT) is currently indicated to treat anal squamous cell carcinoma (ASCC). Conformal dose delivery and steep dose gradients may cause marginal misses. We analyzed patterns of locoregional...
PURPOSE: Patient-specific quality assurance (QA) for intensity-modulated radiation therapy (IMRT) is a ubiquitous clinical procedure, but conventional methods have often been criticized as being insensitive to errors or less effective than other comm...
PURPOSE: The goal of this study was to generate a large treatment plan database for head and neck (H&N) cancer patients that can be considered as the gold standard to train and validate models for knowledge-based (KB) treatment planning and QA. With ...
PURPOSE: To develop an automated treatment planning strategy for external beam intensity-modulated radiation therapy (IMRT), including a deep learning-based three-dimensional (3D) dose prediction and a dose distribution-based plan generation algorith...
PURPOSE: To develop a method for predicting optimal dose distributions, given the planning image and segmented anatomy, by applying deep learning techniques to a database of previously optimized and approved Intensity-modulated radiation therapy trea...
Journal of applied clinical medical physics
Nov 12, 2018
PURPOSE: Convolutional neural networks (CNN) have greatly improved medical image segmentation. A robust model requires training data can represent the entire dataset. One of the differing characteristics comes from variability in patient positioning ...
Accurate clinical target volume (CTV) delineation is essential to ensure proper tumor coverage in radiation therapy. This is a particularly difficult task for head-and-neck cancer patients where detailed knowledge of the pathways of microscopic tumor...
Artificial intelligence (AI) is beginning to transform IMRT treatment planning for head and neck patients. However, the complexity and novelty of AI algorithms make them susceptible to misuse by researchers and clinicians. Understanding nuances of ne...
Journal of applied clinical medical physics
Oct 19, 2018
Knowledge-based planning (KBP) can be used to improve plan quality, planning speed, and reduce the inter-patient plan variability. KPB may also identify and reduce systematic variations in VMAT plans, something very important in multi-institutional c...