AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Towards real-time conformal palliative treatment of spine metastases: A deep learning approach for Hounsfield Unit recovery of cone beam CT images.

Medical physics
BACKGROUND: The extension of onboard cone-beam CT (CBCT) imaging for real-time treatment planning is constrained by limitations in image quality. Synthetic CT (sCT) generation using deep learning provides a potential solution to these limitations.

Two-step beam geometry optimization for volumetric modulated arc therapy gantry angles in breast treatments.

Medical physics
BACKGROUND: In partial arc volumetric modulated arc therapy (VMAT) for treating breast cancer, setting up the limiting gantry positions of the treatment machine is a nontrivial yet repetitive and time-consuming task during planning. Templatized solut...

Smart contours: deep learning-driven internal gross tumor volume delineation in non-small cell lung cancer using 4D CT maximum and average intensity projections.

Radiation oncology (London, England)
BACKGROUND: Delineating the internal gross tumor volume (IGTV) is crucial for the treatment of non-small cell lung cancer (NSCLC). Deep learning (DL) enables the automation of this process; however, current studies focus mainly on multiple phases of ...

Fully Automated Online Adaptive Radiation Therapy Decision-Making for Cervical Cancer Using Artificial Intelligence.

International journal of radiation oncology, biology, physics
BACKGROUND: Interfraction variations during radiation therapy pose a challenge for patients with cervical cancer, highlighting the benefits of online adaptive radiation therapy (oART). However, adaptation decisions rely on subjective image reviews by...

Reduction of the planning target volume with daily online adaptive radiotherapy in bladder cancer.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
INTRODUCTION: External radiation therapy for bladder cancer requires large planning target volumes (PTVs) due to the daily anatomy of the bladder. Online adaptive radiotherapy (oART) can reduce the PTV by considering daily anatomical changes.

Towards improved prescription metrics in novel radiotherapy techniques: a machine learning study.

Physics in medicine and biology
FLASH radiotherapy (RT), microbeam RT (MRT) and minibeam RT (MBRT) are novel RT techniques that have been shown to reduce normal tissue complication probabilities, by modulating the dose distributions through different parameters in space and time. T...

Evaluating the dosimetric and positioning accuracy of a deep learning based synthetic-CT model for liver radiotherapy treatment planning.

Biomedical physics & engineering express
An MRI-only workflow requires synthetic computed tomography (sCT) images to enable dose calculation. This study evaluated the dosimetric and patient positioning accuracy of deep learning-generated sCT for liver radiotherapy.sCT images were generated ...

Portal dose image prediction using Monte Carlo generated transmission energy fluence maps of dynamic radiotherapy treatment plans: a deep learning approach.

Biomedical physics & engineering express
This work aims to develop and investigate the feasibility of a hybrid model combining Monte Carlo (MC) simulations and deep learning (DL) to predict electronic portal imaging device (EPID) images based on MC-generated exit phase space energy fluence ...

Rapid dose prediction for lung CyberKnife radiotherapy plans utilizing a deep learning approach by incorporating dosimetric features delivered by noncoplanar beams.

Biomedical physics & engineering express
. The dose distribution of lung cancer patients treated with the CyberKnife (CK) system is influenced by various factors, including tumor location and the direction of CK beams. The objective of this study is to present a deep learning approach that ...

Open-source deep-learning models for segmentation of normal structures for prostatic and gynecological high-dose-rate brachytherapy: Comparison of architectures.

Journal of applied clinical medical physics
BACKGROUND: The use of deep learning-based auto-contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse datasets containi...