This paper presents a novel approach for generating virtual non-contrast planning computed tomography (VNC-pCT) images from contrast-enhanced planning CT (CE-pCT) scans using a deep learning model. Unlike previous studies, which often lacked sufficie...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 27, 2024
BACKGROUND AND PURPOSE: Accurate segmentation of the clinical target volume (CTV) is essential to deliver an effective radiation dose to tumor tissues in cervical cancer radiotherapy. Also, although automated CTV segmentation can reduce oncologists' ...
Journal of radiological protection : official journal of the Society for Radiological Protection
Dec 27, 2024
Artificial intelligence (AI) is transforming medical radiation applications by handling complex data, learning patterns, and making accurate predictions, leading to improved patient outcomes. This article examines the use of AI in optimising radiatio...
BACKGROUND: Modern radiation therapy techniques, such as intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT), use complex fluence modulation strategies to achieve optimal patient dose distribution. Ensuring their ...
To develop a deep reinforcement learning (DRL) agent to self-interact with the treatment planning system to automatically generate intensity modulated radiation therapy (IMRT) treatment plans for head-and-neck (HN) cancer with consistent organ-at-ris...
Journal of applied clinical medical physics
Dec 23, 2024
PURPOSE: To quantitatively evaluate the performance of two types of recurrent neural networks (RNNs), long short-term memory (LSTM) and gated recurrent units (GRU), using Monte Carlo dropout (MCD) to predict pharmacokinetic (PK) parameters from dynam...
Journal of applied clinical medical physics
Dec 20, 2024
PURPOSE: Cardiotoxicity is one of the major concerns in breast cancer treatment, significantly affecting patient outcomes. To improve the likelihood of favorable outcomes for breast cancer survivors, it is essential to carefully balance the potential...
BACKGROUND: Manual contour corrections during fractionated magnetic resonance (MR)-guided radiotherapy (MRgRT) are time-consuming. Conventional population models for deep learning auto-segmentation might be suboptimal for MRgRT at MR-Linacs since the...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 19, 2024
BACKGROUND AND PURPOSE: Knowledge-based planning (KBP) can consistently and efficiently create high-quality Volumetric Arc Therapy (VMAT) plans for cervix cancer. This study describes the cross-validation of two KBP models on geographically distinct ...
Physical and engineering sciences in medicine
Dec 18, 2024
This study examined the characteristics of the broad model (KBP) through a complete open-loop evaluation of volumetric modulated arc therapy (VMAT) plans for prostate cancer in 30 patients at two institutions. KBP, trained using 561 prostate cancer V...
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