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Lipid Metabolism in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis.

Neuroimmunomodulation
OBJECTIVE: Lipid metabolism has been implicated in autoimmune disorders, but its relationship with anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is unclear. This study examined the association of serum lipids with anti-NMDAR encephalit...

[Role of high mobility group protein B1 in 
IL-1α-induced endothelial cell senescence].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
To explore the effect of interleukin-1α (IL-1α) on the senescence of human umbilical vein endothelial cells (HUVECs) and the function of high mobility group protein 1 (HMGB1).
 Methods: HUVECs were randomly divided into a control group, a IL-1α group...

Effect of postweaning heifer development system on average daily gain, pregnancy rates, and subsequent feed efficiency as a pregnant heifer.

Journal of animal science
A 3-yr study utilized 300 Angus-based, spring-born heifers to evaluate postweaning heifer development systems on gain, reproductive performance, and feed efficiency as a pregnant heifer. Heifers were blocked by BW and randomly assigned to graze corn ...

Effects of supplementing calcium salts of polyunsaturated fatty acids to late-gestating beef cows on performance and physiological responses of the offspring.

Journal of animal science
This experiment compared performance and physiological responses of the offspring from cows supplemented with Ca salts of PUFA or SFA + MUFA during late gestation. Ninety-six multiparous, nonlactating, pregnant Angus × Hereford cows were ranked by BW...

Investigation of mechanisms involved in regulation of progesterone catabolism using an overfed versus underfed ewe-lamb model.

Journal of animal science
Alterations in progesterone (P4) catabolism due to high feed intake underlie some effects of nutrition on reproduction. Based on previous research, we hypothesized that high feed intake could potentially increase P4 catabolism, likely due to increase...

Effects of heat stress and dietary zinc source on performance and mammary epithelial integrity of lactating dairy cows.

Journal of dairy science
Dietary Zn and heat stress alter gut integrity in monogastric animals. However, effects of Zn on mammary epithelial integrity in heat-stressed lactating dairy cows have not been studied. Multiparous lactating Holstein cows (n = 72) were randomly assi...

Fetuin-A: A negative acute-phase protein linked to adipose tissue function in periparturient dairy cows.

Journal of dairy science
Fetuin-A (FetA) is a free fatty acid transporter and an acute-phase protein that enhances cellular lipid uptake and lipogenesis. In nonruminants, FetA is involved in lipid-induced inflammation. Despite FetA importance in lipid metabolism and inflamma...

Effects of prepartum dietary cation-anion difference and source of vitamin D in dairy cows: Lactation performance and energy metabolism.

Journal of dairy science
The objectives of this experiment were to evaluate the effects of feeding diets with 2 dietary cation-anion difference (DCAD) levels and supplemented with either cholecalciferol (CH) or calcidiol (CA) during late gestation on lactation performance an...

The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer.

Genome medicine
BACKGROUND: Despite a myriad of attempts in the last three decades to diagnose ovarian cancer (OC) earlier, this clinical aim still remains a significant challenge. Aberrant methylation patterns of linked CpGs analyzed in DNA fragments shed by cancer...

6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression.

Anais da Academia Brasileira de Ciencias
6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice w...