AIMC Topic: Rats

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Characterization and bioactivities of coffee husks extract encapsulated with polyvinylpyrrolidone.

Food research international (Ottawa, Ont.)
Coffee processing generates large amounts of residues of which a portion still has bioactive properties due to their richness in phenolic compounds. This study aimed to obtain a coffee husks extract (CHE) and to encapsulate it (ECHE) with polyvinylpy...

Ultrasound-guided sciatic nerve block in Wistar rat cadavers: Relevant anatomy and injection distribution.

Veterinary anaesthesia and analgesia
OBJECTIVE: To investigate the feasibility of an ultrasound-guided sciatic nerve block by describing the sonoanatomy and comparing the distribution of two volumes of bupivacaine dye solution for nerve staining.

Selective peripheral nerve recording using simulated human median nerve activity and convolutional neural networks.

Biomedical engineering online
BACKGROUND: It is difficult to create intuitive methods of controlling prosthetic limbs, often resulting in abandonment. Peripheral nerve interfaces can be used to convert motor intent into commands to a prosthesis. The Extraneural Spatiotemporal Com...

Dynamic parametric MRI and deep learning: Unveiling renal pathophysiology through accurate kidney size quantification.

NMR in biomedicine
Renal pathologies often manifest as alterations in kidney size, providing a valuable avenue for employing dynamic parametric MRI as a means to derive kidney size measurements for the diagnosis, treatment, and monitoring of renal disease. Furthermore,...

Deep learning structural insights into heterotrimeric alternatively spliced P2X7 receptors.

Purinergic signalling
P2X7 receptors (P2X7Rs) are membrane-bound ATP-gated ion channels that are composed of three subunits. Different subunit structures may be expressed due to alternative splicing of the P2RX7 gene, altering the receptor's function when combined with th...

Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data.

PloS one
The liver is the primary site for the metabolism and detoxification of many compounds, including pharmaceuticals. Consequently, it is also the primary location for many adverse reactions. As the liver is not readily accessible for sampling in humans;...

Automatic segmentation of the interscapular brown adipose tissue in rats based on deep learning using the dynamic magnetic resonance fat fraction images.

Magma (New York, N.Y.)
OBJECTIVE: The study aims to propose an accurate labelling method of interscapular BAT (iBAT) in rats using dynamic MR fat fraction (FF) images with noradrenaline (NE) stimulation and then develop an automatic iBAT segmentation method using a U-Net m...

What is the impact of intraperitoneal surfactant administration against postoperative intraabdominal adhesion formation? an experimental study.

Turkish journal of medical sciences
BACKGROUND/AIM: Surfactant is a surface-active substance that, in addition to its detergent effect, also has effects that reduce inflammation and fibrosis. Because of these effects, it was aimed herein to investigate the effect of intraperitoneal sur...

Utilizing deep learning techniques to improve image quality and noise reduction in preclinical low-dose PET images in the sinogram domain.

Medical physics
BACKGROUND: Low-dose positron emission tomography (LD-PET) imaging is commonly employed in preclinical research to minimize radiation exposure to animal subjects. However, LD-PET images often exhibit poor quality and high noise levels due to the low ...

A systematic review of the development and application of home cage monitoring in laboratory mice and rats.

BMC biology
BACKGROUND: Traditionally, in biomedical animal research, laboratory rodents are individually examined in test apparatuses outside of their home cages at selected time points. However, the outcome of such tests can be influenced by various factors an...