AIMC Topic: Rats

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RVDLAHA: An RISC-V DLA Hardware Architecture for On-Device Real-Time Seizure Detection and Personalization in Wearable Applications.

IEEE transactions on biomedical circuits and systems
Epilepsy is a globally distributed chronic neurological disorder that may pose a threat to life without warning. Therefore, the use of wearable devices for real-time detection and treatment of epilepsy is crucial. Additionally, personalizing disease ...

Prediction of the Extent of Blood-Brain Barrier Transport Using Machine Learning and Integration into the LeiCNS-PK3.0 Model.

Pharmaceutical research
INTRODUCTION: The unbound brain-to-plasma partition coefficient (K) is an essential parameter for predicting central nervous system (CNS) drug disposition using physiologically-based pharmacokinetic (PBPK) modeling. K values for specific compounds ar...

Galactose-Induced Cataracts in Rats: A Machine Learning Analysis.

International journal of medical sciences
Rat models are widely used to study cataracts due to their cost-effectiveness and prominent physiological and genetic similarities to humans The objective of this study was to identify genes involved in cataractogenesis due to galactose exposure in ...

Analysis of Operant Self-administration Behaviors with Supervised Machine Learning: Protocol for Video Acquisition and Pose Estimation Analysis Using DeepLabCut and Simple Behavioral Analysis.

eNeuro
The use of supervised machine learning to approximate poses in video recordings allows for rapid and efficient analysis of complex behavioral profiles. Currently, there are limited protocols for automated analysis of operant self-administration behav...

Prediction of Pharmacoresistance in Drug-Naïve Temporal Lobe Epilepsy Using Ictal EEGs Based on Convolutional Neural Network.

Neuroscience bulletin
Approximately 30%-40% of epilepsy patients do not respond well to adequate anti-seizure medications (ASMs), a condition known as pharmacoresistant epilepsy. The management of pharmacoresistant epilepsy remains an intractable issue in the clinic. Its ...

Development of a Deep Learning Tool to Support the Assessment of Thyroid Follicular Cell Hypertrophy in the Rat.

Toxicologic pathology
Thyroid tissue is sensitive to the effects of endocrine disrupting substances, and this represents a significant health concern. Histopathological analysis of tissue sections of the rat thyroid gland remains the gold standard for the evaluation for a...

Deep Power-Aware Tunable Weighting for Ultrasound Microvascular Imaging.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Ultrasound microvascular imaging (UMI), including ultrafast power Doppler imaging (uPDI) and ultrasound localization microscopy (ULM), obtains blood flow information through plane wave (PW) transmissions at high frame rates. However, low signal-to-no...

Deciphering hub genes and immune landscapes related to neutrophil extracellular traps in rheumatoid arthritis: insights from integrated bioinformatics analyses and experiments.

Frontiers in immunology
BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and progressive joint destruction. Neutrophil extracellular traps (NETs), a microreticular structure formed after neutrophil death, have rece...

Rapid detection of drug abuse via tear analysis using surface enhanced Raman spectroscopy and machine learning.

Scientific reports
With the growing global challenge of drug abuse, there is an urgent need for rapid, accurate, and cost-effective drug detection methods. This study introduces an innovative approach to drug abuse screening by quickly detecting ephedrine (EPH) in tear...