AIMC Topic: Receptors, Cell Surface
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Comprehensive analysis and experimental validation of BST1 as a novel diagnostic biomarker for pediatric sepsis using multiple machine learning algorithms.
European journal of pediatrics
Jun 25, 2025
Bone marrow stromal cell antigen-1 (BST1) expression is elevated in a variety of human diseases, but its relationship with pediatric sepsis is unclear. This study aimed to investigate the expression of BST1 in pediatric sepsis patients and its value ...
An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism.
Scientific reports
Jul 7, 2021
Venous thromboembolism is the third common cardiovascular disease and is composed of two entities, deep vein thrombosis (DVT) and its potential fatal form, pulmonary embolism (PE). While PE is observed in ~ 40% of patients with documented DVT, there ...
Triple-Negative Breast Cancer: A Review of Conventional and Advanced Therapeutic Strategies.
International journal of environmental research and public health
Mar 20, 2020
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to their highly invasive nature and relatively low response to therapeutics...
DeepPhagy: a deep learning framework for quantitatively measuring autophagy activity in .
Autophagy
Jun 20, 2019
Seeing is believing. The direct observation of GFP-Atg8 vacuolar delivery under confocal microscopy is one of the most useful end-point measurements for monitoring yeast macroautophagy/autophagy. However, manually labelling individual cells from larg...
All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences.
Proceedings of the National Academy of Sciences of the United States of America
Apr 9, 2015
Transmembrane β-barrels (TMBs) carry out major functions in substrate transport and protein biogenesis but experimental determination of their 3D structure is challenging. Encouraged by successful de novo 3D structure prediction of globular and α-hel...
ST2 Levels Before and After Treatment of NYHA III and IV Heart Failure.
Acta medica Indonesiana
Oct 1, 2015
AIM: to find whether ST2 can be used to determine clinical improvement in patients with NYHA III and IV heart failure.
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