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Rectal Neoplasms

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Does transanal total mesorectal excision of rectal cancer improve histopathology metrics and/or complication rates? A meta-analysis.

Surgical oncology
BACKGROUND: The aim of this meta-analysis was to determine whether transanal total mesorectal excision (taTME) improves histopathology metrics and/or complication rates when compared to robotic total mesorectal excision (R-TME) of resectable rectal c...

The Pelvis-First Approach for Robotic Proctectomy in Patients with Redundant Abdominal Colon.

Annals of surgical oncology
BACKGROUND: Robotic surgery is increasingly performed for low rectal cancer.1 A redundant sigmoid colon makes retraction and pelvic dissection challenging. We present a 'pelvis-first' approach to robotic proctectomy where pelvic dissection occurs pri...

Neo-adjuvant chemoradiotherapy response prediction using MRI based ensemble learning method in rectal cancer patients.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
OBJECTIVES: The aim of this study was to investigate and validate the performance of individual and ensemble machine learning models (EMLMs) based on magnetic resonance imaging (MRI) to predict neo-adjuvant chemoradiation therapy (nCRT) response in r...

Machine learning for prediction of chemoradiation therapy response in rectal cancer using pre-treatment and mid-radiation multi-parametric MRI.

Magnetic resonance imaging
PURPOSE: To predict the neoadjuvant chemoradiation therapy (CRT) response in patients with locally advanced rectal cancer (LARC) using radiomics and deep learning based on pre-treatment MRI and a mid-radiation follow-up MRI taken 3-4 weeks after the ...

Full convolutional network based multiple side-output fusion architecture for the segmentation of rectal tumors in magnetic resonance images: A multi-vendor study.

Medical physics
PURPOSE: Accurate segmentation of rectal tumors is a basic and crucial task for diagnosis and treatment of rectal cancer. To avoid tedious manual delineation, an automatic rectal tumor segmentation model is proposed.

Impact of nominal photon energies on normal tissue sparing in knowledge-based radiotherapy treatment planning for rectal cancer patients.

PloS one
The interactive adjustment of the optimization objectives during the treatment planning process has made it difficult to evaluate the impact of beam quality exclusively in radiotherapy. Without consensus in the published results, the arbitrary select...

Computer aided quantification of intratumoral stroma yields an independent prognosticator in rectal cancer.

Cellular oncology (Dordrecht, Netherlands)
PURPOSE: Tumor-stroma ratio (TSR) serves as an independent prognostic factor in colorectal cancer and other solid malignancies. The recent introduction of digital pathology in routine tissue diagnostics holds opportunities for automated TSR analysis....

Machine Learning-based Analysis of Rectal Cancer MRI Radiomics for Prediction of Metachronous Liver Metastasis.

Academic radiology
RATIONALE AND OBJECTIVES: To use machine learning-based magnetic resonance imaging radiomics to predict metachronous liver metastases (MLM) in patients with rectal cancer.

A study of positioning orientation effect on segmentation accuracy using convolutional neural networks for rectal cancer.

Journal of applied clinical medical physics
PURPOSE: Convolutional neural networks (CNN) have greatly improved medical image segmentation. A robust model requires training data can represent the entire dataset. One of the differing characteristics comes from variability in patient positioning ...

Towards a modular decision support system for radiomics: A case study on rectal cancer.

Artificial intelligence in medicine
Following the personalized medicine paradigm, there is a growing interest in medical agents capable of predicting the effect of therapies on patients, by exploiting the amount of data that is now available for each patient. In disciplines like oncolo...