AIMC Topic: Risk Assessment

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Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties.

The Journal of toxicological sciences
An in silico method for predicting percutaneous absorption of cosmetic ingredients was developed by using artificial neural network (ANN) analysis to predict the human skin permeability coefficient (log Kp), taking account of the physicochemical prop...

In silico risk assessment for skin sensitization using artificial neural network analysis.

The Journal of toxicological sciences
The sensitizing potential of chemicals is usually identified and characterized using in vivo methods such as the murine local lymph node assay (LLNA). Due to regulatory constraints and ethical concerns, alternatives to animal testing are needed to pr...

Development of QSAR models using artificial neural network analysis for risk assessment of repeated-dose, reproductive, and developmental toxicities of cosmetic ingredients.

The Journal of toxicological sciences
Use of laboratory animals for systemic toxicity testing is subject to strong ethical and regulatory constraints, but few alternatives are yet available. One possible approach to predict systemic toxicity of chemicals in the absence of experimental da...

Evaluation of a hospital admission prediction model adding coded chief complaint data using neural network methodology.

European journal of emergency medicine : official journal of the European Society for Emergency Medicine
OBJECTIVE: Our objective was to apply neural network methodology to determine whether adding coded chief complaint (CCC) data to triage information would result in an improved hospital admission prediction model than one without CCC data.

Ambient Temperature Change Increases in Stroke Onset: Analyses Based on the Japanese Regional Metrological Measurements.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
BACKGROUND: Relationships between various climate factors and stroke have long been a subject of investigation. The present study investigated in a single medical center the effects of periodic temperature changes on the onset of intracerebral hemorr...

Swarm intelligence applied to the risk evaluation for congenital heart surgery.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Particle Swarm Optimization is an optimization technique based on the positions of several particles created to find the best solution to a problem. In this work we analyze the accuracy of a modification of this algorithm to classify the levels of ri...

Thermal Signal Analysis for Breast Cancer Risk Verification.

Studies in health technology and informatics
Breast cancer is the second most common cancer in the world. Currently, there are no effective methods to prevent this disease. However, early diagnosis increases chances of remission. Breast thermography is an option to be considered in screening st...

Post-operative bleeding risk stratification in cardiac pulmonary bypass patients using artificial neural network.

Annals of clinical and laboratory science
The prediction of bleeding risk in cardiopulmonary bypass (CPB) patients plays a vital role in their postoperative management. Therefore, an artificial neural network (ANN) to analyze intra-operative laboratory data to predict postoperative bleeding ...

Knowledge-Based Personal Health System to empower outpatients of diabetes mellitus by means of P4 Medicine.

Methods in molecular biology (Clifton, N.J.)
Diabetes Mellitus (DM) affects hundreds of millions of people worldwide and it imposes a large economic burden on healthcare systems. We present a web patient empowering system (PHSP4) that ensures continuous monitoring and assessment of the health s...

Pilot licensing after aortic valve surgery.

The Journal of heart valve disease
BACKGROUND AND AIM OF THE STUDY: Bicuspid aortic valve is the most common congenital heart malformation, and a high percentage of patients with this condition will develop complications over time. It is rare that pilots undergo aortic valve surgery, ...