AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

RNA, Long Noncoding

Showing 141 to 150 of 157 articles

Clear Filters

DeepLGP: a novel deep learning method for prioritizing lncRNA target genes.

Bioinformatics (Oxford, England) Aug 15, 2020
MOTIVATION: Although long non-coding RNAs (lncRNAs) have limited capacity for encoding proteins, they have been verified as biomarkers in the occurrence and development of complex diseases. Recent wet-lab experiments have shown that lncRNAs function ...
Deep Learning Gene Regulatory Networks RNA, Long Noncoding Neural Networks, Computer
View on PubMed DOI

Screening key lncRNAs with diagnostic and prognostic value for head and neck squamous cell carcinoma based on machine learning and mRNA-lncRNA co-expression network analysis.

Cancer biomarkers : section A of Disease markers Jan 1, 2020
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the seventh most common type of cancer around the world. The aim of this study was to seek the long non-coding RNAs (lncRNAs) acting as diagnostic and prognostic biomarker of HNSCC.
Humans Machine Learning Prognosis RNA, Messenger Gene Expression Regulation, Neoplastic Squamous Cell Carcinoma of Head and Neck Biomarkers, Tumor Gene Regulatory Networks Computational Biology High-Throughput Screening Assays Head and Neck Neoplasms RNA, Long Noncoding
View on PubMed DOI

Recent Advances on the Semi-Supervised Learning for Long Non-Coding RNA-Protein Interactions Prediction: A Review.

Protein and peptide letters Jan 1, 2020
In recent years, more and more evidence indicates that long non-coding RNA (lncRNA) plays a significant role in the development of complex biological processes, especially in RNA progressing, chromatin modification, and cell differentiation, as well ...
Models, Molecular Computer Simulation Supervised Machine Learning Protein Binding Humans RNA-Binding Proteins Databases, Nucleic Acid RNA, Long Noncoding Software Proteins Databases, Protein
View on PubMed DOI

circDeep: deep learning approach for circular RNA classification from other long non-coding RNA.

Bioinformatics (Oxford, England) Jan 1, 2020
MOTIVATION: Over the past two decades, a circular form of RNA (circular RNA), produced through alternative splicing, has become the focus of scientific studies due to its major role as a microRNA (miRNA) activity modulator and its association with va...
Reproducibility of Results Deep Learning Computational Biology RNA, Long Noncoding RNA, Circular
View on PubMed DOI

[Methylation level of MEG3 and semen quality].

Zhonghua nan ke xue = National journal of andrology Nov 1, 2019
OBJECTIVE: To study the relationship between semen quality and the methylation level of maternally expressed gene 3 (MEG3) in sperm.
Sperm Motility RNA, Long Noncoding Humans Methylation CpG Islands Male Semen Analysis Genomic Imprinting Spermatozoa
View on PubMed

Uncovering the mouse olfactory long non-coding transcriptome with a novel machine-learning model.

DNA research : an international journal for rapid publication of reports on genes and genomes Aug 1, 2019
Very little is known about long non-coding RNAs (lncRNAs) in the mammalian olfactory sensory epithelia. Deciphering the non-coding transcriptome in olfaction is relevant because these RNAs have been shown to play a role in chromatin modification and ...
Olfactory Receptor Neurons Vomeronasal Organ Female Animals Male Transcriptome Mice RNA, Long Noncoding Machine Learning
View on PubMed DOI

DeepCNPP: Deep Learning Architecture to Distinguish the Promoter of Human Long Non-Coding RNA Genes and Protein-Coding Genes.

Studies in health technology and informatics Jul 4, 2019
Promoter region of protein-coding genes are gradually being well understood, yet no comparable studies exist for the promoter of long non-coding RNA (lncRNA) genes which has emerged as a global potential regulator in multiple cellular process and dif...
Humans RNA, Long Noncoding Computational Biology Machine Learning Promoter Regions, Genetic Models, Theoretical Deep Learning
View on PubMed DOI

[Effects of long non-coding RNA RP1-90L14.1 on the biological behaviors of cancer prostate LNCaP cells and its regulating mechanisms].

Zhonghua nan ke xue = National journal of andrology Mar 1, 2019
OBJECTIVE: To investigate the effects of long non-coding RNA RP1-90L14.1 on the proliferation, migration and invasion of prostate cancer LNCaP cells and the expressions of GRIN2A and BACE2.
Cell Proliferation Amyloid Precursor Protein Secretases Humans Cell Movement RNA, Long Noncoding Cell Line, Tumor Aspartic Acid Endopeptidases Male Neoplasm Invasiveness Prostatic Neoplasms Gene Expression Regulation, Neoplastic Receptors, N-Methyl-D-Aspartate Transfection
View on PubMed

Enrichment of Up-regulated and Down-regulated Gene Clusters Using Gene Ontology, miRNAs and lncRNAs in Colorectal Cancer.

Combinatorial chemistry & high throughput screening Jan 1, 2019
AIM AND OBJECTIVE: It is interesting to find the gene signatures of cancer stages based on the omics data. The aim of study was to evaluate and to enrich the array data using gene ontology and ncRNA databases in colorectal cancer.
MicroRNAs RNA, Long Noncoding Multigene Family High-Throughput Screening Assays Down-Regulation Up-Regulation Gene Expression Profiling Gene Regulatory Networks Databases, Genetic Humans Gene Ontology Colorectal Neoplasms
View on PubMed DOI

Screening key lncRNAs for human lung adenocarcinoma based on machine learning and weighted gene co-expression network analysis.

Cancer biomarkers : section A of Disease markers Jan 1, 2019
BACKGROUND: Lung adenocarcinoma (LUAD) accounts for a significant proportion of lung cancer and there have been few diagnostic and therapeutic targets for LUAD due to the lack of specific biomarker. The aim of this study was to identify key long non-...
Gene Regulatory Networks RNA, Long Noncoding Female Adenocarcinoma of Lung Humans Male Machine Learning Gene Expression Profiling
View on PubMed DOI
Popular Topics
Recent Journals