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Sarcoma

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Development of a prognostic Neutrophil Extracellular Traps related lncRNA signature for soft tissue sarcoma using machine learning.

Frontiers in immunology
BACKGROUND: Soft tissue sarcoma (STS) is a highly heterogeneous musculoskeletal tumor with a significant impact on human health due to its high incidence and malignancy. Long non-coding RNA (lncRNA) and Neutrophil Extracellular Traps (NETs) have cruc...

The automatic diagnosis artificial intelligence system for preoperative magnetic resonance imaging of uterine sarcoma.

Journal of gynecologic oncology
OBJECTIVE: Magnetic resonance imaging (MRI) is efficient for the diagnosis of preoperative uterine sarcoma; however, misdiagnoses may occur. In this study, we developed a new artificial intelligence (AI) system to overcome the limitations of requirin...

Radiomics and artificial intelligence in malignant uterine body cancers: Protocol for a systematic review.

PloS one
INTRODUCTION: Uterine body cancers (UBC) are represented by endometrial carcinoma (EC) and uterine sarcoma (USa). The clinical management of both is hindered by the complex classification of patients into risk classes. This problem could be simplifie...

Combining multiparametric MRI features-based transfer learning and clinical parameters: application of machine learning for the differentiation of uterine sarcomas from atypical leiomyomas.

European radiology
OBJECTIVES: To explore the feasibility and effectiveness of machine learning (ML) based on multiparametric magnetic resonance imaging (mp-MRI) features extracted from transfer learning combined with clinical parameters to differentiate uterine sarcom...

Research on imbalance machine learning methods for MRWI soft tissue sarcoma data.

BMC medical imaging
BACKGROUND: Soft tissue sarcoma is a rare and highly heterogeneous tumor in clinical practice. Pathological grading of the soft tissue sarcoma is a key factor in patient prognosis and treatment planning while the clinical data of soft tissue sarcoma ...

High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders.

Cell death & disease
Multiple cancer types have limited targeted therapeutic options, in part due to incomplete understanding of the molecular processes underlying tumorigenesis and significant intra- and inter-tumor heterogeneity. Identification of novel molecular bioma...

Development of a deep learning method for improving diagnostic accuracy for uterine sarcoma cases.

Scientific reports
Uterine sarcomas have very poor prognoses and are sometimes difficult to distinguish from uterine leiomyomas on preoperative examinations. Herein, we investigated whether deep neural network (DNN) models can improve the accuracy of preoperative MRI-b...

A deep learning model for accurately predicting cancer-specific survival in patients with primary bone sarcoma of the extremity: a population-based study.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
PURPOSE: Primary bone and joint sarcomas of the long bone are relatively rare neoplasms with poor prognosis. An efficient clinical tool that can accurately predict patient prognosis is not available. The current study aimed to use deep learning algor...

Radiomics and artificial intelligence for soft-tissue sarcomas: Current status and perspectives.

Diagnostic and interventional imaging
This article proposes a summary of the current status of the research regarding the use of radiomics and artificial intelligence to improve the radiological assessment of patients with soft tissue sarcomas (STS), a heterogeneous group of rare and ubi...

Artificial intelligence large language model ChatGPT: is it a trustworthy and reliable source of information for sarcoma patients?

Frontiers in public health
INTRODUCTION: Since its introduction in November 2022, the artificial intelligence large language model ChatGPT has taken the world by storm. Among other applications it can be used by patients as a source of information on diseases and their treatme...