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Schizophrenia

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Prediction of physical violence in schizophrenia with machine learning algorithms.

Psychiatry research
Patients with schizophrenia have been shown to have an increased risk for physical violence. While certain features have been identified as risk factors, it has been difficult to integrate these variables to identify violent patients. The present stu...

Multivariate patterns of EEG microstate parameters and their role in the discrimination of patients with schizophrenia from healthy controls.

Psychiatry research
Quasi-stable electrical fields in the EEG, called microstates carry information on the dynamics of large scale brain networks. Using machine learning techniques, we explored whether abnormalities in microstates can be used to classify patients with s...

Detecting Abnormal Brain Regions in Schizophrenia Using Structural MRI via Machine Learning.

Computational intelligence and neuroscience
Utilizing neuroimaging and machine learning (ML) to differentiate schizophrenia (SZ) patients from normal controls (NCs) and for detecting abnormal brain regions in schizophrenia has several benefits and can provide a reference for the clinical diagn...

Will machine learning applied to neuroimaging in bipolar disorder help the clinician? A critical review and methodological suggestions.

Bipolar disorders
OBJECTIVES: The existence of anatomofunctional brain abnormalities in bipolar disorder (BD) is now well established by magnetic resonance imaging (MRI) studies. To create diagnostic and prognostic tools, as well as identifying biologically valid subt...

Feature optimization method for machine learning-based diagnosis of schizophrenia using magnetoencephalography.

Journal of neuroscience methods
BACKGROUND: When many features and a small number of clinical data exist, previous studies have used a few top-ranked features from the Fisher's discriminant ratio (FDR) for feature selection. However, there are many similarities between selected fea...

Pragmatics, Theory of Mind and executive functions in schizophrenia: Disentangling the puzzle using machine learning.

PloS one
OBJECTIVE: Schizophrenia is associated with a severe impairment in the communicative-pragmatic domain. Recent research has tried to disentangle the relationship between communicative impairment and other domains usually impaired in schizophrenia, i.e...

Diagnosing schizophrenia with network analysis and a machine learning method.

International journal of methods in psychiatric research
OBJECTIVE: Schizophrenia is a chronic and debilitating neuropsychiatric disorder. It has been suggested that impaired brain connectivity underlies the pathophysiology of schizophrenia. Network analysis has thus recently emerged in the field of schizo...

A Multidimensional Neural Maturation Index Reveals Reproducible Developmental Patterns in Children and Adolescents.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Adolescence is a time of extensive neural restructuring, leaving one susceptible to atypical development. Although neural maturation in humans can be measured using functional and structural MRI, the subtle patterns associated with the initial stages...