AIMC Topic: Serum Amyloid P-Component

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A machine learning model including pentraxin-3 as predictor of outcomes in community-acquired pneumonia.

Journal of translational medicine Oct 31, 2025
BACKGROUND: The clinical diagnosis, severity assessment, and outcome prognostication of community-acquired pneumonia (CAP) remain challenging due to the complex disease pathophysiology. Accurate outcome prediction is crucial for optimizing patient ma...
Humans Machine Learning Prospective Studies Biomarkers Prognosis Female Aged Male Middle Aged ROC Curve Treatment Outcome Pneumonia C-Reactive Protein Area Under Curve Serum Amyloid P-Component Community-Acquired Infections Community-Acquired Pneumonia
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Establishment of a nomogram model based on immune-related genes using machine learning for aortic dissection diagnosis and immunomodulation assessment.

International journal of medical sciences Jan 21, 2025
The clinical manifestation of aortic dissection (AD) is complex and varied, making early diagnosis crucial for patient survival. This study aimed to identify immune-related markers to establish a nomogram model for AD diagnosis. Three datasets from G...
Humans Machine Learning Male Gene Expression Profiling Protein Interaction Maps Gene Regulatory Networks Nomograms Databases, Genetic C-Reactive Protein Aortic Dissection Immunomodulation Tissue Inhibitor of Metalloproteinase-1 Serum Amyloid P-Component Chemokine CXCL1
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Serum Amyloid P-component Level May be a Biomarker for Lung Toxicities and Overall Survival after Thoracic Radiotherapy for Non-small Cell Lung Cancer.

Clinical laboratory Nov 1, 2016
BACKGROUND: Serum amyloid P-component (SAP) contributes to the clearance of apoptotic cells. As one of the main acute-phase reactants, SAP regulates key aspects of inflammation and sets a threshold for immune cell activation. This study aimed to inve...
Humans Risk Factors Biomarkers, Tumor Time Factors Lung Neoplasms Enzyme-Linked Immunosorbent Assay Treatment Outcome Carcinoma, Non-Small-Cell Lung Predictive Value of Tests Pulmonary Fibrosis Proportional Hazards Models Multivariate Analysis Kaplan-Meier Estimate Radiation Pneumonitis Serum Amyloid P-Component
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