AIMC Topic: Immunomodulation

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Establishment of a nomogram model based on immune-related genes using machine learning for aortic dissection diagnosis and immunomodulation assessment.

International journal of medical sciences Jan 21, 2025
The clinical manifestation of aortic dissection (AD) is complex and varied, making early diagnosis crucial for patient survival. This study aimed to identify immune-related markers to establish a nomogram model for AD diagnosis. Three datasets from G...
Nomograms Databases, Genetic C-Reactive Protein Protein Interaction Maps Gene Regulatory Networks Tissue Inhibitor of Metalloproteinase-1 Serum Amyloid P-Component Chemokine CXCL1 Aortic Dissection Immunomodulation Humans Male Gene Expression Profiling Machine Learning
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Predicting the immunomodulatory activity of probiotic lactic acid bacteria using supervised machine learning in a Cornu aspersum snail model.

Fish & shellfish immunology Jul 23, 2024
In the process of screening for probiotic strains, there are no clearly established bacterial phenotypic markers which could be used for the prediction of their in vivo mechanism of action. In this work, we demonstrate for the first time that Machine...
Machine Learning Animals Helix, Snails Probiotics Snails Lactobacillales Immunity, Innate Immunomodulation
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Human Wharton's Jelly-Derived Stem Cells Display a Distinct Immunomodulatory and Proregenerative Transcriptional Signature Compared to Bone Marrow-Derived Stem Cells.

Stem cells and development Dec 21, 2017
Mesenchymal stromal cells (MSCs) are multipotent stem cells with immunosuppressive and trophic support functions. While MSCs from different sources frequently display a similar appearance in culture, they often show differences in their surface marke...
Mesenchymal Stem Cells Bone Marrow Cells Gene Expression Regulation Cell Line, Tumor Cell Proliferation Cell Adhesion Immunomodulation Gene Ontology Humans Gene Expression Profiling
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New, Immunomodulatory, Oral Nutrition Formula for Use Prior to Surgery in Patients With Head and Neck Cancer: An Exploratory Study.

JPEN. Journal of parenteral and enteral nutrition Dec 12, 2017
BACKGROUND: The perioperative use of immunomodulatory nutrition formulas in patients with head and neck cancer reduces the number of postoperative infections and the length of hospital stay.
Treatment Outcome Head and Neck Neoplasms Administration, Oral Immunomodulation Single-Blind Method Postoperative Complications Humans Enteral Nutrition Length of Stay Female Male Preoperative Care Middle Aged
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Immunomodulation of Zerumbone via Decreasing the Production of Reactive Oxygen Species from Immune Cells.

Pakistan journal of biological sciences : PJBS Jan 1, 2018
BACKGROUND AND OBJECTIVE: Zerumbone has been reported to exert anti-inflammatory, anti-ulcer and anti-hyperglycemic effects but the specific mechanism through which zerumbone exerts its anti-inflammatory action through inhibiting reactive oxygen spec...
Inhibitory Concentration 50 Enzyme Precursors Inflammation Animals Immune System Mice Immunomodulation Neutrophils Tetradecanoylphorbol Acetate Respiratory Burst Luminescence Humans Plant Preparations Dose-Response Relationship, Drug Reactive Oxygen Species Sesquiterpenes Macrophages
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Polysaccharides extracted from the roots of Bupleurum chinense DC modulates macrophage functions.

Chinese journal of natural medicines Dec 1, 2017
The present study aimed to investigate the effects of polysaccharides extracted from Bupleurum chinense DC (BCPs) on macrophage functions. In the in vivo experiment, 1 mL of 5% sodium thioglycollate was injected into the abdomen of the mice on Day 0 ...
Immunomodulation Bupleurum Chemotaxis Polysaccharides Mice Plants, Medicinal Phagocytosis Plant Extracts Immunologic Factors Mice, Inbred BALB C Macrophages Plant Roots Nitric Oxide Cytokines Animals
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