AIMC Topic: Severity of Illness Index

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Identifying New Candidate Predictors of Mortality in Japanese Patients with Severe Drug Eruptions.

Drug safety
UNLABELLED: BACKGROUND AND OBJECTIVES: SCORe of Toxic Epidermal Necrolysis (SCORTEN) and ABCD-10 have been developed as scoring systems for predicting mortality associated with Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). These...

Assessing the performance of artificial intelligence models in evaluating inflammatory skin disease severity: a systematic review and meta-analysis.

The British journal of dermatology
BACKGROUND: Artificial intelligence (AI) applications in dermatology have expanded beyond diagnosis and have shifted towards assessing disease severity.

Prognostication in patients with idiopathic pulmonary fibrosis using quantitative airway analysis from HRCT: a retrospective study.

The European respiratory journal
BACKGROUND: Predicting shorter life expectancy is crucial for prioritising antifibrotic therapy in fibrotic lung diseases (FLDs), where progression varies widely, from stability to rapid deterioration. This heterogeneity complicates treatment decisio...

Decoding chronic stress: From behavioral-molecular dynamics in mice to clinical implications of cortisol and IL-17 in depression severity.

Journal of affective disorders
BACKGROUNDS: The etiology of depression involves chronic stress, a recognized determinant of onset and severity. This study adopts a translational approach, utilizing a mouse model and a clinical cohort to explore the relationship between chronic str...

Two-stage ensemble learning framework for automated classification of keratoconus severity.

Computers in biology and medicine
BACKGROUND AND OBJECTIVE: Accurate staging of keratoconus (KC) is crucial for timely intervention and improving patient quality of life. Unlike prior studies that relied on traditional base machine learning (ML) models, this paper proposes a more adv...

An AI system for continuous knee osteoarthritis severity grading: An anomaly detection inspired approach with few labels.

Artificial intelligence in medicine
The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst also being re...

Risk Stratification of Dengue Cases Requiring Hospitalization.

Journal of medical virology
Dengue pathogenesis involves immune-driven inflammation that contributes to severe disease progression. This study assessed a machine learning model to identify a minimal, yet highly predictive biomarker set, aiming to support clinical decision-makin...

Enhancing HF-DL Model Validation for Liver Fibrosis Staging Through Sample Optimisation and Technical Integration.

Liver international : official journal of the International Association for the Study of the Liver
We read with great interest the article by Zhang et al. The study demonstrates that the deep learning model based on high-frequency ultrasound images significantly outperforms the low-frequency ultrasound model, FIB-4, APRI, and shear wave elastograp...