Precise assessment of toxicological effects remains a key bottleneck in biomedical and environmental health assessments. Traditional toxicology relies on macroscopic end points and manual image analysis, which limit sensitivity to structural damage a...
Surface-enhanced Raman spectroscopy (SERS) is regarded as a powerful tool for rapid drug identification in the liquid phase. However, the implementation of SERS for drug detection in the liquid phase remains constrained by two critical limitations: i...
The emergence of multidrug-resistant pathogens has increased the urgency for alternative treatment options for infections like cystitis. This study focused on the green synthesis of silver nanoparticles and cysteine-conjugated silver nanoparticles ut...
This work introduces a high-performance graphene-silver hybrid metasurface biosensor for the fast and precise detection of COVID-19. Through parametric optimization with COMSOL Multiphysics, the sensor achieves a sensitivity of 400 GHz/RIU, a figure ...
The sensitive detection of drug molecules in complex biological samples presents significant challenges, including weak signal intensity, strong matrix interference, and inefficient access of molecules to SERS hotspots. To address these issues, this ...
Wearable sensors allow non-invasive monitoring of sweat metabolites, but their reliance on molecular recognition elements limits both physiological coverage and temporal resolution. Here we report an all-flexible chronoepifluidic surface-enhanced Ram...
Whole-cell biosensors (WCBs), which detect targeting analytes through cellular responses, have become powerful tools for environmental monitoring. However, existing WCBs often rely on the single-channel low-dimension signal outputs (e.g., fluorescenc...
Journal of chemical information and modeling
Aug 12, 2025
We propose an active learning (AL) framework to develop classical force fields (FFs) that accurately model the potential energy surfaces (PES) of gas/solid atomic-scale complexes. A central challenge is integrating AL with flexible, computationally e...
Conductive hydrogels based on hydroxypropyl methyl cellulose (HPMC) show great potential in flexible sensors due to their low price and good biocompatibility. Nevertheless, the design of such conductive hydrogels with superior flexible deformability,...
Raman spectroscopy is an enticing tool for the rapid identification of pathogenic bacteria and has the potential to meet the demand for early diagnosis and timely treatment of patients. However, it remains a challenge to devise a reliable Raman detec...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.