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Gotcha GPT: Ensuring the Integrity in Academic Writing.

Journal of chemical information and modeling
This application note explores how to address a challenging problem faced by many academics and publishing professionals in recent years: ensuring the integrity of academic writing in universities and publishing houses due to advances in Artificial I...

AI-based open-source software for cephalometric analysis from limited FOV radiographs.

Journal of dentistry
BACKGROUND: Artificial Intelligence (AI) in dental diagnostics is evolving, offering innovative approaches for conducting cephalometric analysis with less manual input and overcoming the limitations of traditional imaging methods. To enhance the diag...

HLA-DR4Pred2: An improved method for predicting HLA-DRB1*04:01 binders.

Methods (San Diego, Calif.)
HLA-DRB1*04:01 is associated with numerous diseases, including sclerosis, arthritis, diabetes, and COVID-19, emphasizing the need to scan for binders in the antigens to develop immunotherapies and vaccines. Current prediction methods are often limite...

LineageFilter: Improved Proteotyping of Complex Samples Using Metaproteomics and Machine Learning.

Journal of proteome research
Metaproteomics is a powerful tool to characterize how microbiota function by analyzing their proteic content by tandem mass spectrometry. Given the complexity of these samples, accurately assessing their taxonomical composition without prior informat...

Assessment of a fully-automated diagnostic AI software in prostate MRI: Clinical evaluation and histopathological correlation.

European journal of radiology
OBJECTIVE: This study aims to evaluate the diagnostic performance of a commercial, fully-automated, artificial intelligence (AI) driven software tool in identifying and grading prostate lesions in prostate MRI, using histopathological findings as the...

Avoidable biopsies? Validating artificial intelligence-based decision support software in indeterminate thyroid nodules.

Surgery
BACKGROUND: Multiple artificial intelligence (AI) systems have been approved to risk-stratify thyroid nodules through sonographic characterization. We sought to validate the ability of one such AI system, Koios DS (Koios Medical, Chicago, IL), to aid...

Real-World evaluation of an AI triaging system for chest X-rays: A prospective clinical study.

European journal of radiology
Chest X-rays (CXRs) are crucial for diagnosing and managing lung conditions. While CXR is a common and cost-effective diagnostic tool, interpreting the high volume of CXRs is challenging due to workforce limitations. Artificial intelligence (AI) offe...

From Noise to Knowledge: Diffusion Probabilistic Model-Based Neural Inference of Gene Regulatory Networks.

Journal of computational biology : a journal of computational molecular cell biology
Understanding gene regulatory networks (GRNs) is crucial for elucidating cellular mechanisms and advancing therapeutic interventions. Original methods for GRN inference from bulk expression data often struggled with the high dimensionality and inhere...

Parameter optimization for stable clustering using FlowSOM: a case study from CyTOF.

Frontiers in immunology
High-dimensional cell phenotyping is a powerful tool to study molecular and cellular changes in health and diseases. CyTOF enables high-dimensional cell phenotyping using tens of surface and intra-cellular markers. To utilize the full potential of Cy...

Data flow in clinical laboratories: could metadata and peridata bridge the gap to new AI-based applications?

Clinical chemistry and laboratory medicine
In the last decades, clinical laboratories have significantly advanced their technological capabilities, through the use of interconnected systems and advanced software. Laboratory Information Systems (LIS), introduced in the 1970s, have transformed ...