Journal of pharmaceutical and biomedical analysis
Nov 15, 2025
On account of the low concentration and complex background, most methods for detecting VOCs in exhaled breath samples required preconcentration prior to instrumental analysis. In the current study, a simple and rapid method is developed for analyzing...
Mortality rates have risen dramatically in recent years due to the misuse of fentanyl and its analogs. Due to the easy synthesis and rapid emergence of various fentanyl analogs, an accurate detection model is particularly desirable. The existing clas...
Selection of the optimal makeup solvent composition is critical for achieving sensitive and reproducible ionization in supercritical fluid chromatography-mass spectrometry (SFC-MS). This study investigated the ionization processes in a spray-based io...
Journal of the American Society for Mass Spectrometry
Jun 4, 2025
In nontargeted spatial metabolomics, accurate annotation is crucial for understanding metabolites' biological roles and spatial patterns. MS mass spectrometry imaging (MSI) coverage is often incomplete or nonexistent, resulting in many unknown featur...
OBJECTIVE: Construct a prediction model for lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) using Probe Electrospray Ionization Mass Spectrometry (PESI - MS) combined with artificial intelligence (AI), to assist in the preoperative p...
Mass spectrometry is one of the most effective analytical methods for unknown compound identification. By comparing observed / spectra with a database of experimentally determined spectra, this process identifies compound(s) in any given sample. Unkn...
A new UPLC-MS/MS method (method A), for simultaneous determination of alogliptin (ALN) and metformin (MET) in their recently approved pharmaceutical combination Kazano® tablets, was developed and compared to a new UHPLC-UV method (method B). Concerni...
Rinsho byori. The Japanese journal of clinical pathology
Sep 1, 2015
Conventionally, a definitive diagnosis of cancer is derived from histopathological diagnostics based on morphological criteria that are difficult to standardize on a quantifiable basis. On the other hand, while molecular tumor markers and blood bioch...
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