AIMC Topic: Spectrophotometry

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An in vitro assay and artificial intelligence approach to determine rate constants of nanomaterial-cell interactions.

Scientific reports
In vitro assays and simulation technologies are powerful methodologies that can inform scientists of nanomaterial (NM) distribution and fate in humans or pre-clinical species. For small molecules, less animal data is often needed because there are a ...

Classification of cow milk using artificial neural network developed from the spectral data of single- and three-detector spectrophotometers.

Food chemistry
Spectra data from two instruments (UV-Vis/NIR and FT-NIR) consisting of three and one detectors, respectively, were employed in order to discriminate the geographical origin of milk as a way to detect adulteration. Initially, principal component anal...

Estimating the Temperature of Heat-exposed Bone via Machine Learning Analysis of SCI Color Values: A Pilot Study.

Journal of forensic sciences
Determining maximum heating temperatures of burnt bones is a long-standing problem in forensic science and archaeology. In this pilot study, controlled experiments were used to heat 14 fleshed and defleshed pig vertebrae (wet bones) and archaeologica...

Innovative spectrophotometric methods for simultaneous estimation of the novel two-drug combination: Sacubitril/Valsartan through two manipulation approaches and a comparative statistical study.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Different innovative spectrophotometric methods were introduced for the first time for simultaneous quantification of sacubitril/valsartan in their binary mixture and in their combined dosage form without prior separation through two manipulation app...

Spectrophotometric determination of fluoxetine by molecularly imprinted polypyrrole and optimization by experimental design, artificial neural network and genetic algorithm.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
A selective method based on molecularly imprinted polymer (MIP) solid-phase extraction (SPE) using UV-Vis spectrophotometry as a detection technique was developed for the determination of fluoxetine (FLU) in pharmaceutical and human serum samples. Th...

New model for prediction binary mixture of antihistamine decongestant using artificial neural networks and least squares support vector machine by spectrophotometry method.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In the present study, artificial neural networks (ANNs) and least squares support vector machines (LS-SVM) as intelligent methods based on absorption spectra in the range of 230-300nm have been used for determination of antihistamine decongestant con...

Validated Spectrophotometric and RP-HPLC-DAD Methods for the Determination of Ursodeoxycholic Acid Based on Derivatization with 2-Nitrophenylhydrazine.

Journal of AOAC International
This work describes the development, validation, and application of two simple, accurate, and reliable methods for the determination of ursodeoxycholic acid (UDCA) in bulk powder and in pharmaceutical dosage forms. The carboxylic acid group in UDCA w...

Spectrophotometric determination of synthetic colorants using PSO-GA-ANN.

Food chemistry
Four common food colorants, containing tartrazine, sunset yellow, ponceau 4R and methyl orange, are simultaneously quantified without prior chemical separation. In this study, an effective artificial neural network (ANN) method is designed for modeli...

Artificial neural network assisted kinetic spectrophotometric technique for simultaneous determination of paracetamol and p-aminophenol in pharmaceutical samples using localized surface plasmon resonance band of silver nanoparticles.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Spectrophotometric analysis method based on the combination of the principal component analysis (PCA) with the feed-forward neural network (FFNN) and the radial basis function network (RBFN) was proposed for the simultaneous determination of paraceta...

Novel reliable model by integrating the discrete wavelet transform with fuzzy intelligent systems for the simultaneous spectrophotometric determination of anticancer drug and anti-acquired resistance drug in biological samples.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Simultaneous measurement of drugs used to treat cancer and medications prescribed to overcome resistance to these drugs is important in pharmaceutical formulations and biological samples. In this study, a spectrophotometric method with a hybrid of di...