INTRODUCTION: The substantial case detection gap in the field of child tuberculosis (TB) disease is largely driven by inadequate diagnostic tools and approaches. Chest radiographs (CXRs) remain a key component in the evaluation of children and young ...
Tuberculosis (TB) remains a major global health challenge, causing approximately 1.4 million deaths annually. In many high-burden regions, limited access to expert radiological interpretation leads to delayed or missed diagnoses. To address this, we ...
Six months of drug treatment is standard of care for drug-sensitive pulmonary tuberculosis (TB). Understanding the factors determining the length of treatment required for durable cure would allow individualization of treatment durations. We conducte...
In clinical practice for the diagnosis of pulmonary tuberculosis (PTB), bronchoscopy is typically performed under airway surface anaesthesia. The effectiveness of this anaesthesia is closely associated with the smoothness of bronchoscopy diagnosis, a...
The role of chromatin regulators (CRs) in mediating epigenetic changes during tuberculosis (TB) infection remains poorly understood. This study aimed to determine the efficacy of CRs in diagnosing TB and characterizing its heterogeneity. GSE83456 dat...
Air pollution is the fifth and sixth leading risk factor for global mortality and reduced life expectancy. Studies have established a link between atmospheric pollution and the incidence, hospitalization, and mortality rates of pulmonary tuberculosis...
Tuberculosis (TB) remains a major global health burden, particularly in low-resource, high-prevalence regions. Pediatric TB diagnosis poses challenges with non-specific symptoms and less distinct radiological manifestations than adult TB. Many affect...
BACKGROUND: Tuberculosis (TB) diagnosis remains a challenge, particularly in low-resource settings. Point-of-care ultrasound (POCUS) has shown promise, but most studies focus on HIV-infected populations. In the case of TB, data on lung ultrasound (LU...
INTRODUCTION: Diagnosing pulmonary tuberculosis (PTB) in children is challenging owing to paucibacillary disease, non-specific symptoms and signs and challenges in microbiological confirmation. Chest X-ray (CXR) interpretation is fundamental for diag...
In this study, we investigated the correlation between air pollution indicators and pulmonary tuberculosis (TB) incidence and mortality rates across provincial administrative regions of China from January 2013 to December 2020 to develop predictive m...
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