INTRODUCTION: Hippocampal atrophy is an established biomarker for conversion from the normal ageing process to developing cognitive impairment and dementia. This study used a novel hypothesis-free machine-learning approach, to uncover potential risk ...
BACKGROUND: Cardiovascular disease is a leading cause of global death. Prospective population-based studies have found that changes in retinal microvasculature are associated with the development of coronary artery disease. Recently, artificial intel...
Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current diagnosti...
The concept of biological age has emerged as a measurement that reflects physiological and functional decline with ageing. Here we aimed to develop a deep neural network (DNN) model that predicts biological age from optical coherence tomography (OCT)...
The journals of gerontology. Series B, Psychological sciences and social sciences
Jun 10, 2025
OBJECTIVES: Device-based sedentary time shows a nonlinear association with incident dementia among older adults. However, associations between sedentary time and cognitive performance have been inconsistent. We examined potential nonlinear associatio...
The brain undergoes complex but normal structural changes during the aging process in healthy adults, whereas deviations from the normal aging patterns of the brain can be indicative of various conditions as well as an increased risk for the developm...
Studies in health technology and informatics
May 15, 2025
Accelerometer data obtained with wearable devices over extended periods of time provides objective, valuable information on activity behavior. Building on previous work to derive easy-to-interpret activity parameters - the Activity Types from Long-te...
European journal of preventive cardiology
Apr 22, 2025
AIMS: Most prediction models for coronary artery disease (CAD) compile biomedical and behavioural risk factors using linear multivariate models. This study explores the potential of integrating positive psychosocial factors (PPFs), including happines...
European heart journal. Cardiovascular Imaging
Sep 30, 2024
AIMS: Standard methods of heart chamber volume estimation in cardiovascular magnetic resonance (CMR) typically utilize simple geometric formulae based on a limited number of slices. We aimed to evaluate whether an automated deep learning neural netwo...
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Aug 21, 2024
Fracture prediction is essential in managing patients with osteoporosis and is an integral component of many fracture prevention guidelines. We aimed to identify the most relevant clinical fracture risk factors in contemporary populations by training...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.