AIMC Topic: Unsupervised Machine Learning

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Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.

SLAS discovery : advancing life sciences R & D
There has been an increase in the use of machine learning and artificial intelligence (AI) for the analysis of image-based cellular screens. The accuracy of these analyses, however, is greatly dependent on the quality of the training sets used for bu...

An unsupervised deep learning technique for susceptibility artifact correction in reversed phase-encoding EPI images.

Magnetic resonance imaging
Echo planar imaging (EPI) is a fast and non-invasive magnetic resonance imaging technique that supports data acquisition at high spatial and temporal resolutions. However, susceptibility artifacts, which cause the misalignment to the underlying struc...

Exploration of critical care data by using unsupervised machine learning.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Identification of subgroups may be useful to understand the clinical characteristics of ICU patients. The purposes of this study were to apply an unsupervised machine learning method to ICU patient data to discover subgroups...

Efficient Position Decoding Methods Based on Fluorescence Calcium Imaging in the Mouse Hippocampus.

Neural computation
Large-scale fluorescence calcium imaging methods have become widely adopted for studies of long-term hippocampal and cortical neuronal dynamics. Pyramidal neurons of the rodent hippocampus show spatial tuning in freely foraging or head-fixed navigati...

DART: Domain-Adversarial Residual-Transfer networks for unsupervised cross-domain image classification.

Neural networks : the official journal of the International Neural Network Society
The accuracy of deep learning (e.g., convolutional neural networks) for an image classification task critically relies on the amount of labeled training data. Aiming to solve an image classification task on a new domain that lacks labeled data but ga...

Generative Adversarial Networks are special cases of Artificial Curiosity (1990) and also closely related to Predictability Minimization (1991).

Neural networks : the official journal of the International Neural Network Society
I review unsupervised or self-supervised neural networks playing minimax games in game-theoretic settings: (i) Artificial Curiosity (AC, 1990) is based on two such networks. One network learns to generate a probability distribution over outputs, the ...

Top-down machine learning approach for high-throughput single-molecule analysis.

eLife
Single-molecule approaches provide enormous insight into the dynamics of biomolecules, but adequately sampling distributions of states and events often requires extensive sampling. Although emerging experimental techniques can generate such large dat...

Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification.

Clinical epigenetics
BACKGROUND: Machine learning is a sub-field of artificial intelligence, which utilises large data sets to make predictions for future events. Although most algorithms used in machine learning were developed as far back as the 1950s, the advent of big...

Interpatient Similarities in Cardiac Function: A Platform for Personalized Cardiovascular Medicine.

JACC. Cardiovascular imaging
OBJECTIVES: The authors applied unsupervised machine-learning techniques for integrating echocardiographic features of left ventricular (LV) structure and function into a patient similarity network that predicted major adverse cardiac event(s) (MACE)...

Unsupervised Machine Learning Reveals Novel Traumatic Brain Injury Patient Phenotypes with Distinct Acute Injury Profiles and Long-Term Outcomes.

Journal of neurotrauma
The heterogeneity of traumatic brain injury (TBI) remains a core challenge for the success of interventional clinical trials. Data-driven approaches for patient stratification may help to identify TBI patient phenotypes during the acute injury period...