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Virus Diseases

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Controlling testing volume for respiratory viruses using machine learning and text mining.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Viral testing for pediatric inpatients with respiratory symptoms is common, with considerable associated charges. In an attempt to reduce testing volumes, we studied whether data available at the time of admission could aid in identifying children wi...

AIDS causes sharp rise in number of Brazilian orphans.

AIDS weekly plus
An estimated 183,000 Brazilian children are at risk of losing their mothers to AIDS, according to a survey released. The survey, sponsored by UNICEF, was conducted by the John Snow Institute. Survey estimates are that 10,600 Brazilian children younge...

Automatic tissue characterization of air trapping in chest radiographs using deep neural networks.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Significant progress has been made in recent years for computer-aided diagnosis of abnormal pulmonary textures from computed tomography (CT) images. Similar initiatives in chest radiographs (CXR), the common modality for pulmonary diagnosis, are much...

Lyapunov functional for virus infection model with diffusion and state-dependent delays.

Mathematical biosciences and engineering : MBE
In this paper, a virus dynamics model with diffusion, state-dependent delays and a general nonlinear functional response is investigated. At first, the dynamical system is constructed on a nonlinear metric space. Then the stability of the interior eq...

A generalizable 29-mRNA neural-network classifier for acute bacterial and viral infections.

Nature communications
Improved identification of bacterial and viral infections would reduce morbidity from sepsis, reduce antibiotic overuse, and lower healthcare costs. Here, we develop a generalizable host-gene-expression-based classifier for acute bacterial and viral ...

Machine learning in the clinical microbiology laboratory: has the time come for routine practice?

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
BACKGROUND: Machine learning (ML) allows the analysis of complex and large data sets and has the potential to improve health care. The clinical microbiology laboratory, at the interface of clinical practice and diagnostics, is of special interest for...

Towards development of a novel universal medical diagnostic method: Raman spectroscopy and machine learning.

Chemical Society reviews
Many problems exist within the myriad of currently employed screening and diagnostic methods. Further, an incredibly wide variety of procedures are used to identify an even greater number of diseases which exist in the world. There is a definite unme...

Using the antibody-antigen binding interface to train image-based deep neural networks for antibody-epitope classification.

PLoS computational biology
High-throughput B-cell sequencing has opened up new avenues for investigating complex mechanisms underlying our adaptive immune response. These technological advances drive data generation and the need to mine and analyze the information contained in...

Current status and future perspectives of computational studies on human-virus protein-protein interactions.

Briefings in bioinformatics
The protein-protein interactions (PPIs) between human and viruses mediate viral infection and host immunity processes. Therefore, the study of human-virus PPIs can help us understand the principles of human-virus relationships and can thus guide the ...