AIMC Topic: Young Adult

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Surgical and radiological outcomes of giant cell tumor of the bone: prognostic value of Campanacci grading and selective use of denosumab.

Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
BACKGROUND: Advancements in diagnostic and therapeutic modalities for giant cell tumors of bone (GCTB) have introduced molecular and radiological tools that refine clinical decision-making. H3.3 G34W immunohistochemical staining has become a routine ...

Prediction of High-Dose Methotrexate Blood Concentration in Osteosarcoma Patients Using Machine Learning.

Drug design, development and therapy
INTRODUCTION: High-dose methotrexate is a typical chemotherapy that is widely used in the treatment of osteosarcoma. However, the unique dose-response relationship of methotrexate makes its treatment window relatively narrow, and its clinical use is ...

Visualizing functional network connectivity differences using an explainable machine-learning method.

Physiological measurement
. Functional network connectivity (FNC) estimated from resting-state functional magnetic resonance imaging showed great information about the neural mechanism in different brain disorders. But previous research has mainly focused on standard statisti...

Empowering Data Sharing in Neuroscience: A Deep Learning Deidentification Method for Pediatric Brain MRIs.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Privacy concerns, such as identifiable facial features within brain scans, have hindered the availability of pediatric neuroimaging data sets for research. Consequently, pediatric neuroscience research lags adult counterparts,...

Reirradiation for recurrent glioblastoma: the significance of the residual tumor volume.

Journal of neuro-oncology
PURPOSE: Recurrent glioblastoma has a poor prognosis, and its optimal management remains unclear. Reirradiation (re-RT) is a promising treatment option, but long-term outcomes and optimal patient selection criteria are not well established.

A deep learning algorithm for automated adrenal gland segmentation on non-contrast CT images.

BMC medical imaging
BACKGROUND: The adrenal glands are small retroperitoneal organs, few reference standards exist for adrenal CT measurements in clinical practice. This study aims to develop a deep learning (DL) model for automated adrenal gland segmentation on non-con...

Identification of relevant features using SEQENS to improve supervised machine learning models predicting AML treatment outcome.

BMC medical informatics and decision making
BACKGROUND AND OBJECTIVE: This study has two main objectives. First, to evaluate a feature selection methodology based on SEQENS, an algorithm for identifying relevant variables. Second, to validate machine learning models that predict the risk of co...

Is AI the future of evaluation in medical education?? AI vs. human evaluation in objective structured clinical examination.

BMC medical education
BACKGROUND: Objective Structured Clinical Examinations (OSCEs) are widely used in medical education to assess students' clinical and professional skills. Recent advancements in artificial intelligence (AI) offer opportunities to complement human eval...

Perspectives and Experiences With Large Language Models in Health Care: Survey Study.

Journal of medical Internet research
BACKGROUND: Large language models (LLMs) are transforming how data is used, including within the health care sector. However, frameworks including the Unified Theory of Acceptance and Use of Technology highlight the importance of understanding the fa...

Functional blepharoptosis screening with generative augmented deep learning from external ocular photography.

Orbit (Amsterdam, Netherlands)
PURPOSE: To develop and validate a deep learning model for the detection of functional blepharoptosis from external ocular photographs, and to quantify the impact of augmenting the training data with synthetic images on model performance.