Expert review of clinical pharmacology
Aug 19, 2025
INTRODUCTION: Anticholinergic burden (AChB), the cumulative impact of medications with anticholinergic properties, is a modifiable risk factor linked to cognitive impairment, falls, and functional decline in older adults. Yet despite the availability... read more
BACKGROUND: Artificial intelligence-powered chatbots (AI-PCs) are increasingly integrated into educational settings, including health care disciplines. Despite their potential to enhance learning, limited research has investigated physiotherapy (PT) ... read more
CanAssist Breast (CAB), an immunohistochemistry (IHC) and artificial intelligence-based prognostic test, was developed on Hormone receptor-positive (HR +), HER2/neu-negative (HER2-) breast tumors from Indian patients and validated in retrospective gl... read more
Condensers with helical tubes have received much attention in diverse industries. The optimal design of the mentioned equipment necessitates predictive tools for calculating the condensation heat transfer coefficient (HTC). However, literature models... read more
This paper investigated 4D supply chain finance system utilizing fractal fractional derivatives with the generalized Mittag-Leffler kernel. The model incorporates key interactions between customer demand, distributor inventory, and retailer orders, c... read more
Longitudinal serological proteomic dynamics during antiviral therapy (AVT) in chronic hepatitis B (CHB) patients with liver fibrosis remain poorly characterized. Here, using four-dimensional data-independent acquisition mass spectrometry (4D-DIA-MS),... read more
A self-model is an artificial intelligence that is able to create a continuously updated internal representation of itself. In this paper we use an agent-based architecture to create a 'digital twin self-model', using the example of a small-scale thr... read more
Spiritual health interventions have increasingly been recognized for their potential to improve general health outcomes. This study undertakes a systematic review and meta-analysis to evaluate their effectiveness on patient health in Iran. Data were ... read more
Sepsis is a condition resulting from the uncontrolled immune response to infection, leading to widespread inflammatory damage and potentially fatal organ dysfunction. Currently, there is a lack of specific prevention and treatment strategies for seps... read more
BACKGROUND: Mental health systems worldwide face unprecedented strain due to rising psychological distress, limited access to care, and an insufficient number of trained professionals. Even in high-income countries, the ratio of patients to health ca... read more
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