AI Medical Compendium Journal:
Colloids and surfaces. B, Biointerfaces

Showing 1 to 8 of 8 articles

Design and performance analysis of multi-enzyme activity-doped nanozymes assisted by machine learning.

Colloids and surfaces. B, Biointerfaces
Traditional design approaches for nanozymes typically rely on empirical methods and trial-and-error, which hampers systematic optimization of their structure and performance, thus limiting the efficiency of developing innovative nanozymes. This study...

Clinical translation of nanomedicine with integrated digital medicine and machine learning interventions.

Colloids and surfaces. B, Biointerfaces
Nanomaterials based therapeutics transform the ways of disease prevention, diagnosis and treatment with increasing sophistications in nanotechnology at a breakneck pace, but very few could reach to the clinic due to inconsistencies in preclinical stu...

Biocompatibility of colloidal polypyrrole.

Colloids and surfaces. B, Biointerfaces
The excellent electroconductive properties of polypyrrole (PPy) predetermine its use as cell-instructive or biosensing biomaterial. PPy has potential for application in a physiological environment, and here the cytotoxicity, antioxidant capacity, mod...

Probiotic Escherichia coli Nissle 1917 propelled micro-robot with pH sensitivity for hypoxia targeted intestinal tumor therapy.

Colloids and surfaces. B, Biointerfaces
Poor drug penetration in hypoxia area of solid tumor is a big challenge for intestinal tumor therapy and thus it is crucial to develop an effective strategy to overcome this challenge. Compared with other bacteria used for construction of hypoxia tar...

Comparison of response surface methodology and artificial neural network to optimize novel ophthalmic flexible nano-liposomes: Characterization, evaluation, in vivo pharmacokinetics and molecular dynamics simulation.

Colloids and surfaces. B, Biointerfaces
To improve the topical delivery of pilocarpine hydrochloride (PN) to treat glaucoma, flexible nano-liposomes containing PN (PN-FLs) were prepared, optimized and characterized. Artificial neural network (ANN) and response surface methodology (RSM) wer...

Substrate stiffness affects neural network activity in an extracellular matrix proteins dependent manner.

Colloids and surfaces. B, Biointerfaces
Neuronal growth, differentiation, extension, branching and neural network activity are strongly influenced by the mechanical property of extracellular matrix (ECM). However, the mechanism by which substrate stiffness regulates a neural network activi...

Cholesterol imprinted composite membranes for selective cholesterol recognition from intestinal mimicking solution.

Colloids and surfaces. B, Biointerfaces
Molecularly imprinted polymers which have been extensively investigated as selective adsorbents were constructed using a template molecule during the polymerization to gain template-specific cavities. In this study, we prepared cholesterol imprinted ...

Toltrazuril mixed nanomicelle delivery system based on sodium deoxycholate-Brij C20 polyethylene ether-triton x100: Characterization, solubility, and bioavailability study.

Colloids and surfaces. B, Biointerfaces
Toltrazuril (Tol) is a broad-spectrum anticoccidiosis drug that is widely used in the prevention and treatment of coccidiosis infection in poultry and mammals. However, the drug has poor aqueous solubility (25 °C, 0.41 μg/mL), and its dose escalation...