AI Medical Compendium Journal:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

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Paeonol impacts ovarian cancer cell proliferation, migration, invasion and apoptosis via modulating the transforming growth factor beta/smad3 signaling pathway.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Paeonol (2-hydroxy-4-methoxyphenylacetophenone) is a natural phenolic component isolated from the root bark of peony with multiple pharmacological activities and has been proven to have anti-cancer effects. The objective of this study is to investiga...

Machine learning based deconvolution of microarray atrial samples from atrial fibrillation patients reveals increased fractions of follicular CD4+ T lymphocytes and gamma-delta T cells.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
A potential relationship between T cell immunity and development of atrial fibrillation (AF) has been proposed. Historically in AF patients it has been reported that peripheral blood had elevated CD4+ T cells. However few studies have explored whethe...

Very low-volume interval training improves nonalcoholic fatty liver disease fibrosis score and cardiometabolic health in adults with obesity and metabolic syndrome.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Non-alcoholic fatty liver disease (NAFLD) and cardiometabolic disorders are highly prevalent in obese individuals. Physical exercise is an important element in obesity and metabolic syndrome (MetS) treatment. However, the vast majority of individuals...

Sulodexide modulates the dialysate effect on the peritoneal mesothelium.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Peritoneal membrane damage during chronic peritoneal dialysis is the main cause of that treatment failure. Preservation of the mesothelial cells (MC) is important for the survival of the peritoneum. Evaluation of dialysates effect on the function of ...

Regular cold water swimming during winter time affects resting hematological parameters and serum erythropoietin.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Recreational winter swimming in cold sea water evokes body responses to regularly repeated cold water immersion. However, the understanding of adaptive changes is still limited and data regarding very short-term exposure to severe cold stress are sca...