The journal of prevention of Alzheimer's disease
Mar 8, 2025
BACKGROUND: Integrating machine learning with medical records offers potential for early detection of Alzheimer's disease (AD), enabling timely interventions.
The journal of prevention of Alzheimer's disease
Feb 6, 2025
BACKGROUND: Mild cognitive impairment (MCI) and preclinical MCI (e.g., subjective cognitive decline, SCD) are considered risk states of dementia, such as Alzheimer's Disease (AD). However, it is challenging to accurately predict conversion from norma...
The journal of prevention of Alzheimer's disease
Feb 5, 2025
OBJECTIVE: Due to the recognition for the importance of early intervention in Alzheimer's disease (AD), it is important to focus on prevention and treatment strategies for mild cognitive impairment (MCI). This study aimed to establish a risk predicti...
The journal of prevention of Alzheimer's disease
Jan 1, 2025
BACKGROUND: Protein abundance levels, sensitive to both physiological changes and external interventions, are useful for assessing the Alzheimer's disease (AD) risk and treatment efficacy. However, identifying proteomic prognostic markers for AD is c...
The journal of prevention of Alzheimer's disease
Jan 1, 2025
BACKGROUND: Investigators conducting clinical trials have an ethical, scientific, and regulatory obligation to protect the safety of trial participants. Traditionally, safety monitoring includes manual review and coding of adverse event data by exper...
The journal of prevention of Alzheimer's disease
Jan 1, 2024
Alzheimer's is a degenerative brain cell disease that affects around 5.8 million people globally. The progressive neurodegenerative disease known as Alzheimer's Disease (AD), affects the frontal cortex, the part of the brain in charge of memory, lang...
The journal of prevention of Alzheimer's disease
Jan 1, 2021
BACKGROUND: It is important to use outcome measures for novel interventions in Alzheimer's disease (AD) that capture the research participants' views of effectiveness. The electronic Person-Specific Outcome Measure (ePSOM) development programme is un...
The journal of prevention of Alzheimer's disease
Jan 1, 2020
The neuropsychological scores and Functional Activities Questionnaire (FAQ) are significant to measure the cognitive and functional domain of the patients affected by the Alzheimer's Disease. Further, there are standardized dataset available today th...
The journal of prevention of Alzheimer's disease
Jan 1, 2019
BACKGROUND: Recruiting patients for clinical trials of potential therapies for Alzheimer's disease (AD) remains a major challenge, with demand for trial participants at an all-time high. The AD treatment R and D pipeline includes around 112 agents. I...