AIMC Topic: Adrenal Cortex Hormones

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High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status.

Cell reports Apr 13, 2021
Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-resistant ...
Humans Machine Learning Asthma Severity of Illness Index Interleukin-10 Macrophages Adrenal Cortex Hormones Anti-Asthmatic Agents Interferon-gamma Bronchoalveolar Lavage Fluid Interleukin-7 Receptors, IgE Adaptive Immunity Immunologic Memory Immunity, Innate CD8-Positive T-Lymphocytes CD4-Positive T-Lymphocytes Gene Expression Regulation Proteomics Signal Transduction Gene Expression Profiling Case-Control Studies
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Predicting Corticosteroid-Free Biologic Remission with Vedolizumab in Crohn's Disease.

Inflammatory bowel diseases May 18, 2018
BACKGROUND AND AIMS: Vedolizumab (VDZ) is effective for Crohn's disease (CD) but costly and is slow to produce remission. Early knowledge of whether vedolizumab is likely to succeed is valuable for physicians, patients, and insurers.
Remission Induction Adrenal Cortex Hormones C-Reactive Protein Area Under Curve Crohn Disease Gastrointestinal Agents Antibodies, Monoclonal, Humanized Biological Products ROC Curve Treatment Outcome Adult Male Middle Aged Cohort Studies Female Young Adult Humans Machine Learning
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Predicting Hospitalization and Outpatient Corticosteroid Use in Inflammatory Bowel Disease Patients Using Machine Learning.

Inflammatory bowel diseases Dec 19, 2017
BACKGROUND: Inflammatory bowel disease (IBD) is a chronic disease characterized by unpredictable episodes of flares and periods of remission. Tools that accurately predict disease course would substantially aid therapeutic decision-making. This study...
Immunosuppressive Agents Retrospective Studies Machine Learning Adrenal Cortex Hormones Female Area Under Curve Humans Inflammatory Bowel Diseases Outpatients Male Risk Factors Middle Aged Hospitalization
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Increasing our knowledge base of asthma.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology Dec 1, 2017
United States Knowledge Bases Patient Outcome Assessment Adrenal Cortex Hormones Animals Health Knowledge, Attitudes, Practice Pulmonary Disease, Chronic Obstructive Asthma Humans Phenotype
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