Non-invasive preoperative assessment of HER2 status is critical for identifying candidates for targeted therapy and personalizing treatment strategies in endometrial cancer (EC). This study aims to assess the preoperative value of multiparametric mag...
Signal transduction and targeted therapy
Oct 13, 2025
Nearly 30% of patients with schizophrenia respond inadequately to current antipsychotics, with unclear markers and mechanisms of antipsychotic efficacy. A total of 208 patients with schizophrenia treated for 6 weeks with oral paliperidone were analyz...
PURPOSE: Obstructive sleep apnea (OSA) is highly prevalent among obese individuals, with a complex and bidirectional relationship wherein obesity not only serves as a primary risk factor for OSA but also exacerbates its severity. This interconnection...
This study aims to enhance individual hypertension risk prediction in Indonesia using machine learning (ML) models. The research investigates the predictive accuracy of models with and without incorporating personal hypertension history, seeking to u...
Talk and Deteriorate refers to a clinical course where a patient is able to speak immediately after a traumatic brain injury but subsequently deteriorates in consciousness. Talk and Deteriorate outcomes are poor, and reliable prediction may help impr...
BACKGROUND: Spinal angiography (SA) remains the gold standard for evaluating spinal cord vasculature, but traditional approaches expose operators and patients to significant ionizing radiation. Robotic-assisted platforms offer potential advantages th...
Understanding vaccine hesitancy is a critical public health challenge, yet traditional statistical methods often fail to capture the complex drivers behind it. This study uses COVID-19 vaccine hesitancy in a rural population as a case study to demons...
BACKGROUND AND OBJECTIVES: Over half of all deaths after traumatic brain injury (TBI) follow the decision to withdraw life-sustaining therapy (WLST). Despite recent improvements in TBI mortality, rates of WLST have remained unchanged, potentially ref...
Aldehyde compounds are significantly associated with diabetes mellitus. The metabolic profile of aldehydes can enhance understanding of the mechanisms underlying development of diabetes. This study employed a pair of stable isotope labeling (SIL) rea...
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