AIMC Topic: Adult

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Machine learning-based prediction of N2 lymph node metastasis in non-small cell lung cancer.

BMC pulmonary medicine
BACKGROUND: Lung cancer is a leading cause of cancer-related mortality worldwide. Accurate staging of mediastinal lymph nodes is a crucial step in determining appropriate treatment approaches. Current noninvasive diagnostic methods do not provide suf...

AI-driven chemotoxicity prediction in colorectal cancer: impact of race, SDOH, and biological aging.

BMC cancer
BACKGROUND: Patients with colorectal cancer (CRC) often experience chemotoxicity that impacts treatment adherence, survival, and quality of life. Early screening for chemotoxicity risk is vital, yet comprehensive predictive models are lacking. The ob...

The diagnostic value of serum cysteine protease inhibitor (CST4) in colorectal cancer: a preliminary study.

BMC gastroenterology
BACKGROUND: CST4 is associated with various cancers but its diagnostic value in colorectal cancer (CRC) has not been clearly established. This study aims to further validate the diagnostic value of CST4 in colorectal cancer using random forest models...

Support vector machine-based preoperative identification of IDH-Mutant low-grade gliomas in adult gliomas using clinical features.

BMC neurology
BACKGROUND: The preoperative identification of (isocitrate dehydrogenase) IDH-mutant low-grade gliomas (LGGs) is critical for personalized treatment planning. We aimed to develop a streamlined machine-learning model using key clinical features for ra...

Predicting hematologic toxicity in advanced cervical cancer patients using interpretable machine learning models based on radiomics and dosimetrics.

BMC cancer
BACKGROUND AND OBJECTIVES: Hematologic toxicity (HT) is a common and serious side effect for advanced cervical cancer patients undergoing chemoradiotherapy. Accurately predicting HT can significantly improve patient management and treatment outcomes....

Machine learning-assisted screening of clinical features for predicting difficult-to-treat rheumatoid arthritis.

Scientific reports
To identify clinical features that predict the risk of meeting difficult-to-treat (D2T) rheumatoid arthritis (RA) definition in advance. This retrospective analysis included RA patients from the ATTRA registry who initiated biologic (b-) or targeted ...

The power of justifications to repair human-robot trust, even under moral disagreement.

Scientific reports
To avert criticism and losses of trust, robots that adopt social roles in the near future will have to be aware of and follow the norms of the communities in which they operate. However, norms often conflict with one another, and resolving such confl...

Reconfiguration of functional brain hierarchy in schizophrenia.

Translational psychiatry
The multidimensional nature of schizophrenia requires a comprehensive exploration of the functional and structural brain networks. While prior research has provided valuable insights into these aspects, our study goes a step further to investigate th...

Role of the rostral anterior cingulate cortex in emotion processing in Treatment Resistant Depression.

Translational psychiatry
The rostral anterior cingulate cortex (rACC) has been identified as a key region in treatment-resistant depression (TRD), potentially influencing the adaptive interplay between the default mode network and other critical neural networks. This study a...

Predicting six-month mortality in adult hemophagocytic lymphohistiocytosis with machine learning: a prognostic approach utilizing laboratory data.

Annals of medicine
BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is associated with high mortality rates. This study was conducted to develop and validate a predictive model for adult HLH patients at high risk of six months mortality using machine learning (ML) ...