AIMC Topic: Aged, 80 and over

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Multi-omics study of molecular and genetic bases of orthostatic hypotension.

Clinical epigenetics
Orthostatic hypotension is a sharp decrease in blood pressure when an individual transitions from a supine to an upright position. OH affects at least 30% of older adults. It is attributed to the dysfunction of the autonomic innervation and decreased...

Machine learning-based risk prediction model for cognitive dysfunction in elderly individuals.

PloS one
BACKGROUND: With the advancement of globalization, the prevalence of cognitive dysfunction in the elderly population has risen significantly. Early intervention may dramatically alleviate the disease burden and reduce economic costs associated with c...

Leading predictors and their associations with combination opioid pain therapy in older adults with cancer: Application of machine learning approaches.

PloS one
Combined use of opioids and other pharmacological therapies used for pain management, such as non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, gabapentinoids, and/or skeletal muscle relaxants (SMRs), in older adult cancer survivors ca...

Continuous tobacco smoking increases mortality in diffuse large B-cell lymphoma but not follicular lymphoma, a Finnish population-based study.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Tobacco smoking was prognostic in B-cell lymphomas in the pre-rituximab era, but the association with modern treatment, stage, subtypes, and survival outcomes remains unclear. Patient/material and methods: All patients with di...

Site-specific pain dynamics: associations between accelerometer-measured physical activity patterns and pain in older adults.

The journal of headache and pain
BACKGROUND: Physical activity (PA) has emerged as a promising non-pharmacological intervention for pain management, the relationship between objectively measured PA patterns and multi-site pain remains poorly understood. This exploratory study invest...

Real-world evaluation of the accuracy of the Viz.AI automated intracranial hemorrhage volume calculation tool.

Journal of neurointerventional surgery
BACKGROUND: Appropriate management of spontaneous intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) requires rapid, accurate volume estimation. Viz.AI has developed an artificial intelligence (AI)-powered ICH calculation tool that ...

Garden classification of femoral neck fracture using deep-learning algorithm.

Scientific reports
The Garden classification, based on X-ray interpretation and established over 50 years ago, remains the standard clinical classification system for femoral neck fractures (FNFs). Yet, this classification has a high interobserver variability of 70%. W...

Predicting and explaining life satisfaction among older adults using tree-based ensemble models and SHAP: Evidence from the digital divide survey.

PloS one
As digital transformation continues to penetrate various sectors of society, the issue of the digital divide has become increasingly prominent. Against the backdrop of accelerating population aging, the barriers that older adults face in accessing an...

Machine learning-based mortality risk prediction model for elderly diabetic patients with non-ST-segment elevation myocardial infarction using MIMIC-IV database.

Scientific reports
Non-ST-elevation myocardial infarction (NSTEMI) in elderly diabetic patients presents unique challenges in risk assessment and prognosis prediction. This study aimed to develop and validate a machine learning-based mortality risk prediction model for...

Deep learning-based artificial intelligence models predict survival in patients with oral cavity squamous cell carcinoma.

Scientific reports
Traditional survival predictions for oral squamous cell carcinoma (OSCC) rely on TNM staging, which lacks individualized prognostic value. Clinical factors such as performance status, age, sex, and lifestyle affect outcomes but are underrepresented i...