AIMC Topic: Aged, 80 and over

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High-acceleration pancreatobiliary MRI with deep learning-based super-resolution reconstruction for evaluating presumed pancreatic intraductal papillary mucinous neoplasm.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: To evaluate the feasibility and diagnostic utility of a deep learning (DL)-based super-resolution (SR) reconstruction algorithm applied to pancreatobiliary MRI for assessing pancreatic intraductal papillary mucinous neoplasms (IPMNs).

Dual-task walking for early detection of Alzheimer's disease: comparative analysis of tasks using whole-body gait variables.

BMC geriatrics
BACKGROUND: The worldwide rise in dementia creates an urgent need for screening methods that are both sensitive and easy to administer. Dual-task walking-requiring people to walk while performing a second cognitive or motor task-meets these criteria ...

Screening mild cognitive impairment using aspects of personal, social, and functional lifestyle: Machine Learning Approaches.

PloS one
OBJECTIVE: Mild cognitive impairment (MCI) signals cognitive decline beyond normal aging and increases dementia risk. Early identification enables preventative interventions, yet many patients in primary care go undetected. This study examines whethe...

Enhancing explainability of random survival forests in predicting stent patency risk for malignant colonic obstruction.

BMC gastroenterology
BACKGROUND: This study aims to enhance the explainability and predictive accuracy of the Random Survival Forest (RSF) algorithm in predicting stent patency risk for patients with malignant colonic obstruction.

Multimodal integration of plasma biomarkers, MRI, and genetic risk to predict cerebral amyloid burden in Alzheimer's disease.

NeuroImage
Alzheimer's disease (AD), the most prevalent neurodegenerative disorder, is marked by the accumulation of amyloid-β (Aβ) plaques. Although cerebral Aβ positron emission tomography (Aβ-PET) remains the gold standard for assessing cerebral Aβ burden, i...

Gaining Brain Insights by Tapping into the Black Box: Linking Structural MRI Features to Age and Cognition using Shapley-Based Interpretation Methods.

Neuroinformatics
Global interpretability in machine learning holds great potential for extracting meaningful insights from neuroimaging data to improve our understanding of brain function. Although various approaches exist to identify key contributing features at bot...

Aging as an active player in Alzheimer's disease classification: Insights from feature selection in BrainAge models.

NeuroImage
BACKGROUND: BrainAge models estimate the biological age of the brain using neuroimaging or clinical features, making them promising tools for studying neurodegenerative diseases like Alzheimer's disease. However, the reliance of BrainAge models on ne...

Visuospatial performance and its neural substrates in Dementia with Lewy Bodies during a pointing task.

Scientific reports
Dementia with Lewy Bodies (DLB) is characterized by motor and cognitive deficits that often overlap with other neurodegenerative disorders, complicating its diagnosis. This study combined linear mixed-effects modeling and machine learning to investig...