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Machine learning approach for the prediction of 30-day mortality in patients with sepsis-associated delirium.

PloS one
This study aimed to develop models for predicting the 30-day mortality of sepsis-associated delirium (SAD) by multiple machine learning (ML) algorithms. On the whole, a cohort of 3,197 SAD patients were collected from the Medical Information Mart for...

Risk prediction for acute kidney disease and adverse outcomes in patients with chronic obstructive pulmonary disease: an interpretable machine learning approach.

Renal failure
BACKGROUND: Little is known about acute kidney injury (AKI) and acute kidney disease (AKD) in patients with chronic obstructive pulmonary disease (COPD) and COPD mortality based on the acute/subacute renal injury. This study develops machine learning...

Validation of body composition parameters extracted via deep learning-based segmentation from routine computed tomographies.

Scientific reports
Sarcopenia and body composition metrics are strongly associated with patient outcomes. In this study, we developed and validated a flexible, open-access pipeline integrating available deep learning-based segmentation models with pre- and postprocessi...

Leveraging Artificial Intelligence to Uncover Symptom Burden in Palliative Care: Analysis of Nonscheduled Visits Using a Phi-3 Small Language Model.

JCO global oncology
PURPOSE: This study aimed to differentiate nonscheduled visits (NSVs) in an outpatient palliative care setting that are driven by or accompanied by uncontrolled symptoms from those that are administrative or routine, such as prescription refills and ...

DEMENTIA: A Hybrid Attention-Based Multimodal and Multi-Task Learning Framework With Expert Knowledge for Alzheimer's Disease Assessment From Speech.

IEEE journal of biomedical and health informatics
The prevalence of Alzheimer's disease (AD) is rising annually, imposing a severe burden on patients and society. Therefore, assisted AD assessment is crucial. The decline in language function and the cognitive impairment it reflects are key external ...

Prediction of remission of pharmacologically treated psychotic depression: A machine learning approach.

Journal of affective disorders
BACKGROUND: The combination of antidepressant and antipsychotic medication is an effective treatment for major depressive disorder with psychotic features ('psychotic depression'). The present study aims to identify sociodemographic and clinical pred...

Machine Learning Models for Frailty Classification of Older Adults in Northern Thailand: Model Development and Validation Study.

JMIR aging
BACKGROUND: Frailty is defined as a clinical state of increased vulnerability due to the age-associated decline of an individual's physical function resulting in increased morbidity and mortality when exposed to acute stressors. Early identification ...

Data-Driven Prognostication in Distal Medium Vessel Occlusions Using Explainable Machine Learning.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Distal medium vessel occlusions (DMVOs) are estimated to cause acute ischemic stroke in 25%-40% of cases. Prognostic models can inform patient counseling and research by enabling outcome predictions. However, models designed s...

Understanding patterns of loneliness in older long-term care users using natural language processing with free text case notes.

PloS one
Loneliness and social isolation are distressing for individuals and predictors of mortality, yet data on their impact on publicly funded long-term care is limited. Using recent advances in natural language processing (NLP), we analysed pseudonymised ...

Identifying progression subphenotypes of Alzheimer's disease from large-scale electronic health records with machine learning.

Journal of biomedical informatics
OBJECTIVE: Identification of clinically meaningful subphenotypes of disease progression can enhance the understanding of disease heterogeneity and underlying pathophysiology. In this study, we propose a machine learning framework to identify subpheno...