AIMC Topic: Alcoholism

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Model to Predict Progression of Liver Disease in Heavy Drinkers Is Useful Today and Supports the Future of Deep Learning.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Validation of an alcohol misuse classifier in hospitalized patients.

Alcohol (Fayetteville, N.Y.)
BACKGROUND: Current modes of identifying alcohol misuse in hospitalized patients rely on self-report questionnaires and diagnostic codes that have limitations, including low sensitivity. Information in the clinical notes of the electronic health reco...

Salivary microRNAs identified by small RNA sequencing and machine learning as potential biomarkers of alcohol dependence.

Epigenomics
Salivary miRNA can be easily accessible biomarkers of alcohol dependence (AD). The miRNA transcriptome in the saliva of 56 African-Americans (AAs; 28 AD patients/28 controls) and 64 European-Americans (EAs; 32 AD patients/32 controls) was profiled ...

Streptococcus Gallolyticus endocarditis in patient with liver cirrhosis: a case report.

Journal of infection in developing countries
Streptococcus gallolyticus (S. gallolyticus) bacteremia is commonly associated with endocarditis and diseases of gastrointestinal tract, especially with colorectal carcinoma. On the other side, it is rarely connected to liver disease, especially alco...

Resting state connectivity best predicts alcohol use severity in moderate to heavy alcohol users.

NeuroImage. Clinical
BACKGROUND: In the United States, 13% of adults are estimated to have alcohol use disorder (AUD). Most studies examining the neurobiology of AUD treat individuals with this disorder as a homogeneous group; however, the theories of the neurocircuitry ...

Novel Machine Learning Identifies Brain Patterns Distinguishing Diagnostic Membership of Human Immunodeficiency Virus, Alcoholism, and Their Comorbidity of Individuals.

Biological psychiatry. Cognitive neuroscience and neuroimaging
The incidence of alcohol use disorder (AUD) in human immunodeficiency virus (HIV) infection is twice that of the rest of the population. This study documents complex radiologically identified, neuroanatomical effects of AUD+HIV comorbidity by identif...

Machine learning vs addiction therapists: A pilot study predicting alcohol dependence treatment outcome from patient data in behavior therapy with adjunctive medication.

Journal of substance abuse treatment
BACKGROUND AND OBJECTIVES: Clinical staff providing addiction treatment predict patient outcome poorly. Prognoses based on linear statistics are rarely replicated. Addiction is a complex non-linear behavior. Incorporating non-linear models, Machine L...

Methodological Advances in the Study of Hidden Variables: A Demonstration on Clinical Alcohol Use Disorder Data.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Research in the domain of psychopathology has been hindered by hidden variables-variables that are important to understanding and treating psychopathological illnesses but are unmeasured. Recent methodological advances in machine learning have culmin...

Predominant polarity classification and associated clinical variables in bipolar disorder: A machine learning approach.

Journal of affective disorders
BACKGROUND: Bipolar disorder (BD) is a severe psychiatric disorder characterized by periodic episodes of manic and depressive symptomatology. Predominant polarity (PP) appears to be an important specifier of BD. The present study employed machine lea...

Identifying substance use risk based on deep neural networks and Instagram social media data.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Social media may provide new insight into our understanding of substance use and addiction. In this study, we developed a deep-learning method to automatically classify individuals' risk for alcohol, tobacco, and drug use based on the content from th...