Alzheimer disease (AD) is among the most chronic neurodegenerative diseases that threaten global public health. The prevalence of Alzheimer disease and consequently the increased risk of spread all over the world pose a vital threat to human safekeep...
We present open-source tools for three-dimensional (3D) analysis of photographs of dissected slices of human brains, which are routinely acquired in brain banks but seldom used for quantitative analysis. Our tools can: (1) 3D reconstruct a volume fro...
Most classification models for Alzheimer's Diagnosis (AD) do not have specific strategies for individual input samples, leading to the problem of easily overlooking personalized differences between samples. This research introduces a customized dynam...
Longitudinal studies that continuously generate data enable the capture of temporal variations in experimentally observed parameters, facilitating the interpretation of results in a time-aware manner. We propose IL-VIS (incrementally learned visualiz...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jun 12, 2024
Deep-brain Magnetic Stimulation (DMS) can improve the symptoms caused by Alzheimer's disease by inducing rhythmic electric field in the deep brain, and the induced electric field is rhythm-dependent. However, calculating the induced electric field re...
European journal of nuclear medicine and molecular imaging
Jun 11, 2024
INTRODUCTION: Amyloid-β (Aβ) plaques is a significant hallmark of Alzheimer's disease (AD), detectable via amyloid-PET imaging. The Fluorine-18-Fluorodeoxyglucose ([F]FDG) PET scan tracks cerebral glucose metabolism, correlated with synaptic dysfunct...
Physical and engineering sciences in medicine
Jun 11, 2024
Alzheimer's disease (AD) is a progressive and incurable neurologi-cal disorder with a rising mortality rate, worsened by error-prone, time-intensive, and expensive clinical diagnosis methods. Automatic AD detection methods using hand-crafted Electroe...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jun 11, 2024
INTRODUCTION: Most people with Alzheimer's disease and related dementia (ADRD) also suffer from two or more chronic conditions, known as multiple chronic conditions (MCC). While many studies have investigated the MCC patterns, few studies have consid...
The identification of diagnostic and therapeutic biomarkers for Alzheimer's Disease (AD) remains a crucial area of research. In this study, utilizing the Weighted Gene Co-expression Network Analysis (WGCNA) algorithm, we identified RHBDF2 and TNFRSF1...