AIMC Topic: Analgesics, Opioid

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Physicochemical stability of an admixture of lidocaine and ketamine in polypropylene syringe used in opioid-free anaesthesia.

European journal of hospital pharmacy : science and practice
OBJECTIVES: Opioid-free anaesthesia is a treatment strategy of pain management based on the use of drugs such as lidocaine, ketamine and dexmedetomidine that do not interact significantly with opioid receptors. In particular, these drugs are used by ...

Computational Systems Pharmacology-Target Mapping for Fentanyl-Laced Cocaine Overdose.

ACS chemical neuroscience
The United States of America is fighting against one of its worst-ever drug crises. Over 900 people a week die from opioid- or heroin-related overdoses, while millions more suffer from opioid prescription addiction. Recently, drug overdoses caused by...

Artificial Intelligence and Arthroplasty at a Single Institution: Real-World Applications of Machine Learning to Big Data, Value-Based Care, Mobile Health, and Remote Patient Monitoring.

The Journal of arthroplasty
BACKGROUND: Driven by the recent ubiquity of big data and computing power, we established the Machine Learning Arthroplasty Laboratory (MLAL) to examine and apply artificial intelligence (AI) to musculoskeletal medicine.

A Machine Learning Approach for the Detection and Characterization of Illicit Drug Dealers on Instagram: Model Evaluation Study.

Journal of medical Internet research
BACKGROUND: Social media use is now ubiquitous, but the growth in social media communications has also made it a convenient digital platform for drug dealers selling controlled substances, opioids, and other illicit drugs. Previous studies and news i...

Development of Machine Learning Algorithms for Prediction of Sustained Postoperative Opioid Prescriptions After Total Hip Arthroplasty.

The Journal of arthroplasty
BACKGROUND: Postoperative recovery after total hip arthroplasty (THA) can lead to the development of prolonged opioid use but there are few tools for predicting this adverse outcome. The purpose of this study is to develop machine learning algorithms...

Development of machine learning algorithms for prediction of prolonged opioid prescription after surgery for lumbar disc herniation.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Spine surgery has been identified as a risk factor for prolonged postoperative opioid use. Preoperative prediction of opioid use could improve risk stratification, shared decision-making, and patient counseling before surgery.

Machine learning for phenotyping opioid overdose events.

Journal of biomedical informatics
OBJECTIVE: To develop machine learning models for classifying the severity of opioid overdose events from clinical data.

Natural Language Processing-Identified Problem Opioid Use and Its Associated Health Care Costs.

Journal of pain & palliative care pharmacotherapy
Use of prescription opioids and problems of abuse and addiction have increased over the past decade. Claims-based studies have documented substantial economic burden of opioid abuse. This study utilized electronic health record (EHR) data to identify...