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Translating amyloid PET of different radiotracers by a deep generative model for interchangeability.

NeuroImage
It is challenging to compare amyloid PET images obtained with different radiotracers. Here, we introduce a new approach to improve the interchangeability of amyloid PET acquired with different radiotracers through image-level translation. Deep genera...

Somatosensory actuator based on stretchable conductive photothermally responsive hydrogel.

Science robotics
Mimicking biological neuromuscular systems' sensory motion requires the unification of sensing and actuation in a singular artificial muscle material, which must not only actuate but also sense their own motions. These functionalities would be of gre...

Visual interpretation of [F]Florbetaben PET supported by deep learning-based estimation of amyloid burden.

European journal of nuclear medicine and molecular imaging
PURPOSE: Amyloid PET which has been widely used for noninvasive assessment of cortical amyloid burden is visually interpreted in the clinical setting. As a fast and easy-to-use visual interpretation support system, we analyze whether the deep learnin...

PET/CT for Brain Amyloid: A Feasibility Study for Scan Time Reduction by Deep Learning.

Clinical nuclear medicine
PURPOSE: This study was to develop a convolutional neural network (CNN) model with a residual learning framework to predict the full-time 18F-florbetaben (18F-FBB) PET/CT images from corresponding short-time scans.

Performance evaluation in [18F]Florbetaben brain PET images classification using 3D Convolutional Neural Network.

PloS one
High accuracy has been reported in deep learning classification for amyloid brain scans, an important factor in Alzheimer's disease diagnosis. However, the possibility of overfitting should be considered, as this model is fitted with sample data. The...

Deep learning-guided joint attenuation and scatter correction in multitracer neuroimaging studies.

Human brain mapping
PET attenuation correction (AC) on systems lacking CT/transmission scanning, such as dedicated brain PET scanners and hybrid PET/MRI, is challenging. Direct AC in image-space, wherein PET images corrected for attenuation and scatter are synthesized f...

Application of Deep Learning to Predict Standardized Uptake Value Ratio and Amyloid Status on F-Florbetapir PET Using ADNI Data.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Cortical amyloid quantification on PET by using the standardized uptake value ratio is valuable for research studies and clinical trials in Alzheimer disease. However, it is resource intensive, requiring co-registered MR imagi...

The Use of Random Forests to Identify Brain Regions on Amyloid and FDG PET Associated With MoCA Score.

Clinical nuclear medicine
PURPOSE: The aim of this study was to evaluate random forests (RFs) to identify ROIs on F-florbetapir and F-FDG PET associated with Montreal Cognitive Assessment (MoCA) score.

The clinical feasibility of deep learning-based classification of amyloid PET images in visually equivocal cases.

European journal of nuclear medicine and molecular imaging
PURPOSE: Although most deep learning (DL) studies have reported excellent classification accuracy, these studies usually target typical Alzheimer's disease (AD) and normal cognition (NC) for which conventional visual assessment performs well. A clini...

The Use of Random Forests to Classify Amyloid Brain PET.

Clinical nuclear medicine
PURPOSE: To evaluate random forests (RFs) as a supervised machine learning algorithm to classify amyloid brain PET as positive or negative for amyloid deposition and identify key regions of interest for stratification.