AIMC Topic: Carbolines

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Deep learning-guided joint attenuation and scatter correction in multitracer neuroimaging studies.

Human brain mapping May 21, 2020
PET attenuation correction (AC) on systems lacking CT/transmission scanning, such as dedicated brain PET scanners and hybrid PET/MRI, is challenging. Direct AC in image-space, wherein PET images corrected for attenuation and scatter are synthesized f...
Humans Tomography, X-Ray Computed Female Aged Aged, 80 and over Young Adult Adult Male Middle Aged Deep Learning Cognitive Dysfunction Radiopharmaceuticals Aniline Compounds Positron-Emission Tomography Fluorodeoxyglucose F18 Neuroimaging Benzothiazoles Carbolines Dihydroxyphenylalanine
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AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure.

NeuroImage Jul 26, 2017
Utilizing [18F]-AV-1451 tau positron emission tomography (PET) as an Alzheimer disease (AD) biomarker will require identification of brain regions that are most important in detecting elevated tau pathology in preclinical AD. Here, we utilized an uns...
Humans Biomarkers Female Aged Aged, 80 and over Male Middle Aged Disease Progression Cognitive Dysfunction Unsupervised Machine Learning Amyloid beta-Peptides Alzheimer Disease Positron-Emission Tomography tau Proteins Prodromal Symptoms Carbolines
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