Accurate identification of perfluoroalkyl substances (PFASs) is essential for environmental regulation and public health protection. However, current analytical techniques struggle to differentiate PFASs due to their structural similarity. Herein, we...
The inherently constrained regenerative capacity of neuronal tissue poses a major obstacle to repairing traumatic brain injury. While neural stem cell transplantation holds promise, its efficacy is constrained by slow and inefficient neuronal differe...
BACKGROUND: Cells are the fundamental units of life, and understanding their diversity and functionality requires detailed characterization. The rise of single-cell omics data enables this, yet current deep learning approaches lack multi-scale interp...
The primary aim of our study was to address the problem of transcriptomic data complexity by introducing a novel transcriptomic response index (TRI), compressing the entire transcriptomic space into a single variable, and linking it with the inhaled ...
This study presents the first assessment of total mercury (THg) and methylmercury (MeHg) in squids (Todarodes sagittatus, L.), providing insights into contamination levels and their correlation with the geographical origin. A method based on acidic e...
Metabolomics : Official journal of the Metabolomic Society
Oct 18, 2025
INTRODUCTION: The identification of unknown metabolites remains a major challenge in untargeted metabolomics using liquid chromatography-mass spectrometry (LC-MS). This process typically depends on comparing mass spectral or chromatographic data to r...
Spinal cord injury (SCI) represents a notable global health challenge, with neuropathic pain (NP) being a common complication that intensifies patient suffering. Existing research tends to overlook the temporal aspects of NP and fails to offer target...
Applied and environmental microbiology
Oct 17, 2025
The increasing demand for high-quality seafood underscores the significant challenges posed by rampant seafood fraud. This study aimed to identify regional capture biomarkers by using the gut bacteriome of specimens through state-of-the-art long-rea...
Achieving high resolution while minimizing contrast agent dosage remains a key goal, yet a major challenge in contrast-enhanced computed tomography (CT) imaging. Herein, we propose an artificial intelligence-assisted low-dose high atomic number contr...
BACKGROUND: Obesity has emerged as a major global public health challenge and poses a significant threat to human health. Despite extensive research, the mechanisms underlying its pathological progression remain elusive.
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