The internet of things is arriving at the laboratory, connecting instruments for remote control and monitoring. Along with Artificial Intelligence Software to analyse data and design experiments, it could fundamentally change the way research is done...
Opioids are widely used for treating different types of pains, but overuse and abuse of prescription opioids have led to opioid epidemic in the United States. Besides analgesic effects, chronic use of opioid can also cause tolerance, dependence, and ...
O⁶-methylguanine-DNA methyltransferase (MGMT), a unique DNA repair enzyme, can confer resistance to DNA anticancer alkylating agents that modify the O⁶-position of guanine. Thus, inhibition of MGMT activity in tumors has a great interest for cancer r...
Formalin is commonly used as a component of antiparasitic baths in fisheries. In this study the impact of this bath on the immune profile and oxidative stress parameters was evaluated. A formalin bath was prepared in the concentration of 185.3 mg L (...
We show how a multi-resolution network can model the development of acuity and coarse-to-fine processing in the mammalian visual cortex. The network adapts to input statistics in an unsupervised manner, and learns a coarse-to-fine representation by u...
The aim of our study was to investigate the effect of two freezing extenders and two packaging systems on motility, plasma membrane (PM) integrity, and the apoptotic status of frozen-thawed (F-T) spermatozoa of the endangered Old Kladruber stallions....
Preeclampsia (PE), new onset hypertension during pregnancy, is associated with a proinflammatory profile compared to normal pregnancy (NP). We hypothesize that CD4 T cells from PE patient placentas cause PE symptoms during pregnancy compared to those...
Computational intelligence and neuroscience
Nov 1, 2018
The artificial bee colony (ABC) algorithm has become one of the popular optimization metaheuristics and has been proven to perform better than many state-of-the-art algorithms for dealing with complex multiobjective optimization problems. However, th...
Computational intelligence and neuroscience
Nov 1, 2018
This paper presents a novel constraint handling technique for optimum path generation of four-bar linkages using evolutionary algorithms (EAs). Usually, the design problem is assigned to minimize the error between desired and obtained coupler curves ...
Journal of computational biology : a journal of computational molecular cell biology
Oct 31, 2018
The gene ontology (GO) database contains GO terms that describe biological functions of genes. Previous methods for comparing GO terms have relied on the fact that GO terms are organized into a tree structure. Under this paradigm, the locations of tw...
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