AIMC Topic: Animals

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[Effects of treatment on ultrastructure of olfactory bulb and GFAP expression in mice with Parkinson's disease].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion
OBJECTIVE: To observe the effects of treatment on the ultrastructure of olfactory bulb and the expression of substantia nigra glial fibrillary acidic protein (GFAP) in mice with Parkinson's disease (PD) induced by lipopolysaccharide (LPS), and to pr...

Perspectives and applications of machine learning for evolutionary developmental biology.

Molecular omics
Evolutionary Developmental Biology (Evo-Devo) is an ever-expanding field that aims to understand how development was modulated by the evolutionary process. In this sense, "omic" studies emerged as a powerful ally to unravel the molecular mechanisms u...

Blind prediction of protein B-factor and flexibility.

The Journal of chemical physics
The Debye-Waller factor, a measure of X-ray attenuation, can be experimentally observed in protein X-ray crystallography. Previous theoretical models have made strong inroads in the analysis of beta (B)-factors by linearly fitting protein B-factors f...

[Experimental study of a new animal model with trigeminal neuralgia produced by administration of talc to peripheral infraobital nerve in rats].

Shanghai kou qiang yi xue = Shanghai journal of stomatology
PURPOSE: To establish a new animal model of trigeminal neuralgia(TN) produced by administration of talc to peripheral infraobital nerve in rats.

Attractor dynamics of a Boolean model of a brain circuit controlled by multiple parameters.

Chaos (Woodbury, N.Y.)
Studies of Boolean recurrent neural networks are briefly introduced with an emphasis on the attractor dynamics determined by the sequence of distinct attractors observed in the limit cycles. We apply this framework to a simplified model of the basal ...

Global firing rate contrast enhancement in E/I neuronal networks by recurrent synchronized inhibition.

Chaos (Woodbury, N.Y.)
Inhibitory synchronization is commonly observed and may play some important functional roles in excitatory/inhibitory (E/I) neuronal networks. The firing rate contrast enhancement is a general feature of information processing in sensory pathways, an...

A Dynamical Systems Perspective on Flexible Motor Timing.

Trends in cognitive sciences
A hallmark of higher brain function is the ability to rapidly and flexibly adjust behavioral responses based on internal and external cues. Here, we examine the computational principles that allow decisions and actions to unfold flexibly in time. We ...

The anatomy of phenotype ontologies: principles, properties and applications.

Briefings in bioinformatics
The past decade has seen an explosion in the collection of genotype data in domains as diverse as medicine, ecology, livestock and plant breeding. Along with this comes the challenge of dealing with the related phenotype data, which is not only large...