AIMC Topic: Anti-Bacterial Agents

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In vitro cytotoxic, antioxidant, antibacterial and antifungal activity of Saussurea heteromalla indigenous to Pakistan.

Pakistan journal of pharmaceutical sciences Nov 1, 2019
Medicinal plants are proven to reveal vast promising potential providing novel drug candidates to combat health-related problems. The aim of current study is to discover new drug compounds with anti-anticancer, antioxidant, antibacterial and antifung...
Pakistan Mice Plants, Medicinal HeLa Cells Cell Line Bacteria Antifungal Agents Humans Antioxidants Animals Anti-Bacterial Agents Plant Extracts Microbial Sensitivity Tests Candida albicans Cell Line, Tumor NIH 3T3 Cells
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Machine-learning-assisted selection of antibiotic prescription.

Nature medicine Jul 1, 2019
Humans Drug Prescriptions Anti-Bacterial Agents Machine Learning Urinary Tract Infections Drug Resistance, Microbial
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Illuminating the dark side of machine learning.

Nature reviews. Genetics Jul 1, 2019
Machine Learning Anti-Bacterial Agents
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Artificial intelligence can improve decision-making in infection management.

Nature human behaviour Jun 1, 2019
Drug Prescriptions Drug Resistance, Microbial Infections Humans Artificial Intelligence Anti-Bacterial Agents Clinical Decision-Making
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High-throughput screening and Bayesian machine learning for copper-dependent inhibitors of Staphylococcus aureus.

Metallomics : integrated biometal science Mar 20, 2019
One potential source of new antibacterials is through probing existing chemical libraries for copper-dependent inhibitors (CDIs), i.e., molecules with antibiotic activity only in the presence of copper. Recently, our group demonstrated that previousl...
Machine Learning High-Throughput Screening Assays Small Molecule Libraries Staphylococcus aureus Bayes Theorem Copper Anti-Bacterial Agents Microbial Sensitivity Tests
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Bacillus methylotrophicus ASWU-C2, a strain inhabiting hot desert soil, a new source for antibacterial bacillopyrone, pyrophen, and cyclopeptides.

Zeitschrift fur Naturforschung. C, Journal of biosciences Dec 19, 2018
A strain of Bacillus methylotrophicus was isolated from a soil sample collected in Aswan eastern desert, which is known for its extremely arid climate. After fermentation of the strain in liquid culture and subsequent extraction, a bioassay-guided is...
Molecular Conformation Soil Microbiology Bacillus Anti-Bacterial Agents Chromobacterium Phenylalanine Staphylococcus aureus Microbial Sensitivity Tests Peptides, Cyclic Pyrones
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Distribution of main Gram-positive pathogens causing bloodstream infections in United States and European hospitals during the SENTRY Antimicrobial Surveillance Program (2010-2016): concomitant analysis of oritavancin in vitro activity.

Journal of chemotherapy (Florence, Italy) Sep 1, 2018
This study updates the distribution and trends of Gram-positive organisms causing bloodstream infections (BSIs) in the United States (US) and Europe during 2010-2016. In vitro activities of oritavancin and comparators were also evaluated. Staphylococ...
Humans Anti-Bacterial Agents Hospitals Bacteremia United States Europe Gram-Positive Bacterial Infections Lipoglycopeptides Cross Infection Gram-Positive Bacteria
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A pan-genome-based machine learning approach for predicting antimicrobial resistance activities of the Escherichia coli strains.

Bioinformatics (Oxford, England) Jul 1, 2018
MOTIVATION: Antimicrobial resistance (AMR) is becoming a huge problem in both developed and developing countries, and identifying strains resistant or susceptible to certain antibiotics is essential in fighting against antibiotic-resistant pathogens....
Machine Learning Whole Genome Sequencing Genome, Bacterial Anti-Bacterial Agents Drug Resistance, Bacterial Escherichia coli
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Pharmacokinetics of a Single Intramuscular Injection of Long-Acting Ceftiofur Crystalline-Free Acid in Cattle Egrets ( Bubulcus ibis).

Journal of avian medicine and surgery Dec 1, 2017
We determined the pharmacokinetic properties of ceftiofur crystalline-free acid (CCFA), a long-acting antibiotic, after a single intramuscular injection in cattle egrets ( Bubulcus ibis). A dose of 20 mg/kg was administered intramuscularly to 18 bird...
Injections, Intramuscular Female Half-Life Animals Cephalosporins Anti-Bacterial Agents Male Birds Pilot Projects Area Under Curve
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Extracorporeal membrane oxygenation combined with continuous renal replacement therapy in cutaneous burn and inhalation injury caused by hydrofluoric acid and nitric acid.

Medicine Dec 1, 2017
RATIONALE: Hydrofluoric acid (HF) is a highly corrosive agent and can cause corrosive burns. HF can penetrate deeply into tissues through intact skin and the lipid barrier, leading to painful liquefactive necrosis, and inducing hypocalcemia and hypom...
Hydrofluoric Acid Skin Transplantation Critical Care Nitric Acid Renal Replacement Therapy Adult Male Burns, Chemical Extracorporeal Membrane Oxygenation Humans Anti-Bacterial Agents
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