AIMC Topic: Anti-Infective Agents
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The Essential Oils of Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities.
Oxidative medicine and cellular longevity
Dec 18, 2016
The essential oils were isolated by hydrodistillation from the hairy roots (HR) and roots of soil-grown plants (SGR) of and were analyzed by GC-MS method. In the both essential oils 62 compounds were identified. The root essential oils showed the di...
Leuzea
Microbial Sensitivity Tests
Gas Chromatography-Mass Spectrometry
Oils, Volatile
Enterococcus faecalis
Enzyme-Linked Immunosorbent Assay
Saccharomyces cerevisiae
Anti-Infective Agents
Astrocytes
Tumor Necrosis Factor-alpha
Anti-Inflammatory Agents
Interleukin-6
Pseudomonas aeruginosa
Reactive Oxygen Species
Plant Roots
Interleukin-1beta
Candida albicans
Lipopolysaccharides
Cell Line
Humans
Mapping membrane activity in undiscovered peptide sequence space using machine learning.
Proceedings of the National Academy of Sciences of the United States of America
Nov 14, 2016
There are some ∼1,100 known antimicrobial peptides (AMPs), which permeabilize microbial membranes but have diverse sequences. Here, we develop a support vector machine (SVM)-based classifier to investigate ⍺-helical AMPs and the interrelated nature o...
Analytical Method for the Detection of Residual Active Ingredients Found in Neutralized Suspensions of Antimicrobial Products.
Journal of AOAC International
Nov 10, 2016
An analytical method for determining the presence and levels of residual active ingredients found in neutralized suspensions of phenolic and quaternary ammonium salt-based antimicrobial products was developed using solid-phase extraction in combinati...
Evaluation of a machine learning capability for a clinical decision support system to enhance antimicrobial stewardship programs.
Artificial intelligence in medicine
Feb 22, 2016
OBJECTIVE: Antimicrobial stewardship programs have been shown to limit the inappropriate use of antimicrobials. Hospitals are increasingly relying on clinical decision support systems to assist in the demanding prescription reviewing process. In prev...
Formulation of Granules for Site-Specific Delivery of an Antimicrobial Essential Oil to the Animal Intestinal Tract.
Journal of pharmaceutical sciences
Dec 23, 2015
Owing to proliferation of antibiotic-resistant bacteria, the use of antibiotics for livestock growth promotion is banned in many countries and alternatives to in-feed antibiotics are needed. Cinnamon essential oil exhibits strong in vitro antibacteri...
In vitro antimicrobial susceptibility of Mycoplasma bovis clinical isolates recovered from bison (Bison bison).
Canadian journal of microbiology
Dec 18, 2015
Mycoplasma bovis is a pathogen globally affecting cattle and bison herds, causing pneumonia, arthritis, mastitis, abortions, and other symptoms, leading to huge economic losses. Many studies have been done regarding the antimicrobial susceptibility o...
Design, synthesis and antimicrobial activity of 6-N-substituted chitosan derivatives.
Bioorganic & medicinal chemistry letters
Aug 21, 2015
Three novel 6-N-substituted chitosan derivatives were designed and synthesised and characterized by FTIR and NMR. The degree of substitution was calculated by elemental analysis results. The antimicrobial activities of the target compounds were evalu...
Machine learning in burn care and research: A systematic review of the literature.
Burns : journal of the International Society for Burn Injuries
Jul 29, 2015
BACKGROUND: To date, there are no reviews on machine learning (ML) in burn care. Considering the growth of ML in medicine and the complexities and challenges of burn care, this review specializes on ML applications in burn care. The objective was to ...
Prediction of β-lactamase and its class by Chou's pseudo-amino acid composition and support vector machine.
Journal of theoretical biology
Oct 22, 2014
β-Lactam class of antibiotics is used as major therapeutic agent against a number of pathogenic microbes. The widespread and indiscriminate use of antibiotics to treat bacterial infection has prompted evolution of several evading mechanisms from the ...
Harnessing advances in mechanisms, detection, and strategies to combat antimicrobial resistance.
The Science of the total environment
Jun 20, 2025
Antimicrobial resistance (AMR) is a growing global health crisis, threatening the effectiveness of antibiotics and other antimicrobial agents, leading to increased morbidity, mortality, and economic burdens. This review article provides a comprehensi...
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