AIMC Topic: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

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Identification of an ANCA-associated vasculitis cohort using deep learning and electronic health records.

International journal of medical informatics Jan 17, 2025
BACKGROUND: ANCA-associated vasculitis (AAV) is a rare but serious disease. Traditional case-identification methods using claims data can be time-intensive and may miss important subgroups. We hypothesized that a deep learning model analyzing electro...
Humans Middle Aged Deep Learning Cohort Studies Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Female Male Algorithms Electronic Health Records
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Ontology-based integration and querying of heterogeneous rare disease data sources - POLVAS perspective.

Computers in biology and medicine Dec 2, 2024
The integration of rare disease medical databases belonging to different countries is an important problem, as a large number of observations are required for reliable statistical inference of patient data in order to facilitate clinical research. Su...
Registries Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Humans Databases, Factual Information Sources Biological Ontologies Rare Diseases
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Using an artificial intelligence tool incorporating natural language processing to identify patients with a diagnosis of ANCA-associated vasculitis in electronic health records.

Computers in biology and medicine Nov 25, 2023
BACKGROUND: Because anti-neutrophil cytoplasmatic antibody (ANCA)-associated vasculitis (AAV) is a rare, life-threatening, auto-immune disease, conducting research is difficult but essential. A long-lasting challenge is to identify rare AAV patients ...
Software Electronic Health Records Natural Language Processing Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Humans Artificial Intelligence
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Deep learning-based molecular morphometrics for kidney biopsies.

JCI insight Apr 8, 2021
Morphologic examination of tissue biopsies is essential for histopathological diagnosis. However, accurate and scalable cellular quantification in human samples remains challenging. Here, we present a deep learning-based approach for antigen-specific...
Pathology, Clinical Podocytes Deep Learning Case-Control Studies Biopsy Kidney Image Processing, Computer-Assisted Humans Diagnosis, Computer-Assisted Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
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Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis.

Journal of visualized experiments : JoVE Jun 18, 2020
Glomerular cell death is a pathological feature of myeloperoxidase anti neutrophil cytoplasmic antibody associated vasculitis (MPO-AAV). Extracellular deoxyribonucleic acid (ecDNA) is released during different forms of cell death including apoptosis,...
Models, Biological Humans Supervised Machine Learning Animals Peroxidase Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Extracellular Space Glomerulonephritis Extracellular Traps Kidney Glomerulus Male DNA Mice, Inbred C57BL Image Processing, Computer-Assisted Biopsy
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Unveiling the role of oxidative stress in ANCA-associated glomerulonephritis through integrated machine learning and bioinformatics analyses.

Renal failure Dec 1, 2025
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease often leading to rapidly progressive glomerulonephritis. Oxidative stress plays a critical role in the development and progression of ANCA-associ...
Gene Expression Profiling Oxidative Stress Humans Machine Learning Databases, Genetic Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Glomerulonephritis Gene Regulatory Networks Computational Biology
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First Case Report Of Anca-Associated Vasculitis And Anthracosis Coexistence.

Journal of Ayub Medical College, Abbottabad : JAMC Jan 1, 2023
Anthracosis is a type of mild pneumoconiosis secondary to harmless carbon dust deposits. Although anthracosis was previously associated with inhaled coal particles, such as coal workers' pneumoconiosis, this hypothesis was later abandoned; pathology ...
Coal Granuloma Dust Male Positron Emission Tomography Computed Tomography Anthracosis Humans Pneumoconiosis Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Aged
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