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APACHE

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Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency, and liver failure.

Nutrition (Burbank, Los Angeles County, Calif.)
OBJECTIVES: Vitamin D deficiency may be associated with comorbidities and poor prognosis. However, this association in patients in the intensive care unit (ICU) has not been fully elucidated. The aim of this study was to investigate whether the serum...

Level of adrenomedullin in cases with adrenal defficiency and its relation to mortality in patients with sepsis.

Tuberkuloz ve toraks
INTRODUCTION: The aim of this study was to determine the prognostic value of adrenomedullin, after evaluation of adrenal function in sepsis patients. We also evaluated other prognostic factors such as APACHE II score, proBNP, and CRP and their predic...

Towards generalizable entity-centric clinical coreference resolution.

Journal of biomedical informatics
OBJECTIVE: This work investigates the problem of clinical coreference resolution in a model that explicitly tracks entities, and aims to measure the performance of that model in both traditional in-domain train/test splits and cross-domain experiment...

Risk Prediction for Portal Vein Thrombosis in Acute Pancreatitis Using Radial Basis Function.

Annals of vascular surgery
BACKGROUND: Acute pancreatitis (AP) can induce portosplenomesenteric vein thrombosis (PVT), which may generate higher morbidity and mortality. However current diagnostic modalities for PVT are still controversial. In recent decades, artificial neural...

Optimal intensive care outcome prediction over time using machine learning.

PloS one
BACKGROUND: Prognostication is an essential tool for risk adjustment and decision making in the intensive care unit (ICU). Research into prognostication in ICU has so far been limited to data from admission or the first 24 hours. Most ICU admissions ...

Evaluating ICU Clinical Severity Scoring Systems and Machine Learning Applications: APACHE IV/IVa Case Study.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Clinical scoring systems have been developed for many specific applications, yet they remain underutilized for common reasons such as model inaccuracy and difficulty of use. For intensive care units specifically, the Acute Physiology and Chronic Heal...

Comparison of machine learning models for the prediction of mortality of patients with unplanned extubation in intensive care units.

Scientific reports
Unplanned extubation (UE) can be associated with fatal outcome; however, an accurate model for predicting the mortality of UE patients in intensive care units (ICU) is lacking. Therefore, we aim to compare the performances of various machine learning...

An intelligent warning model for early prediction of cardiac arrest in sepsis patients.

Computer methods and programs in biomedicine
BACKGROUND: Sepsis-associated cardiac arrest is a common issue with the low survival rate. Early prediction of cardiac arrest can provide the time required for intervening and preventing its onset in order to reduce mortality. Several studies have be...

Artificial neural networks accurately predict intra-abdominal infection in moderately severe and severe acute pancreatitis.

Journal of digestive diseases
OBJECTIVE: The aim of this study was to evaluate the efficacy of artificial neural networks (ANN) in predicting intra-abdominal infection in moderately severe (MASP) and severe acute pancreatitis (SAP) compared with that of a logistic regression mode...

Development and validation of three machine-learning models for predicting multiple organ failure in moderately severe and severe acute pancreatitis.

BMC gastroenterology
BACKGROUND: Multiple organ failure (MOF) is a serious complication of moderately severe (MASP) and severe acute pancreatitis (SAP). This study aimed to develop and assess three machine-learning models to predict MOF.