Immune checkpoint inhibitor (ICI) therapy is widely used but effective only in a subset of gastric cancers. Epstein-Barr virus (EBV)-positive and microsatellite instability (MSI) / mismatch repair deficient (dMMR) tumors have been reported to be high...
An accurate assessment of preoperative risk may improve use of hospital resources and reduce morbidity and mortality in high-risk surgical patients. This study aims at implementing an automated surgical risk calculator based on Artificial Neural Netw...
Postpartum hemorrhage is the leading cause of maternal morbidity. Clinical prediction of postpartum hemorrhage remains challenging, particularly in the case of a vaginal birth. We studied machine learning models to predict postpartum hemorrhage. Wome...
Machine-assisted treatment selection commonly follows one of two paradigms: a fully personalized paradigm which ignores any possible clustering of patients; or a sub-grouping paradigm which ignores personal differences within the identified groups. W...
The American journal of emergency medicine
Nov 9, 2021
BACKGROUND: The Mortality Probability Model (MPM) is used in research and quality improvement to adjust for severity of illness and can also inform triage decisions. However, a limitation for its automated use or application is that it includes the v...
Ali-M3, an artificial intelligence program, analyzes chest computed tomography (CT) and detects the likelihood of coronavirus disease (COVID-19) based on scores ranging from 0 to 1. However, Ali-M3 has not been externally validated. Our aim was to ev...
Computer methods and programs in biomedicine
Oct 28, 2021
BACKGROUND AND OBJECTIVE: Machine learning and deep learning models are very powerful in predicting the presence of a disease. To achieve good predictions, those models require a certain amount of data to train on, whereas this amount i) is generally...
BACKGROUND: Kidney allograft failure is a common cause of end-stage renal disease. We aimed to develop a dynamic artificial intelligence approach to enhance risk stratification for kidney transplant recipients by generating continuously refined predi...
BACKGROUND: This Phase I, two-part, first-in-human study assessed safety/tolerability and pharmacokinetics/pharmacodynamics of single-ascending doses (SAD) and multiple doses (MD) of the oral toll-like receptor-7 agonist, JNJ-64794964 (JNJ-4964) in h...
Computer methods in biomechanics and biomedical engineering
Oct 25, 2021
Many metrics such as accuracy rate (ACC), area under curve (AUC), Jaccard index (JI), and Cohen's kappa coefficient are available to measure the success of the system in pattern recognition and machine/deep learning systems. However, the superiority ...