AIMC Topic: Arthritis, Rheumatoid

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Recent advances in the use of machine learning and artificial intelligence to improve diagnosis, predict flares, and enrich clinical trials in lupus.

Current opinion in rheumatology
PURPOSE OF REVIEW: Machine learning is a computational tool that is increasingly used for the analysis of medical data and has provided the promise of more personalized care.

Automated evaluation of rheumatoid arthritis from hand radiographs using Machine Learning and deep learning techniques.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
The aim and objectives of the study are as follows: (i) to implement automated patch-based classification of hand X-ray images using modified pre-trained convolutional neural network (CNN) models; (ii) to develop a customized CNN model for automated ...

Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning.

Disease markers
OBJECTIVES: Synovial fibroblasts (SFs) play an important role in the development and progression of rheumatoid arthritis (RA). However, the pathogenic mechanism of SFs remains unclear. The objective of this study was to investigate how neuropeptides ...

A deep learning classification of metacarpophalangeal joints synovial proliferation in rheumatoid arthritis by ultrasound images.

Journal of clinical ultrasound : JCU
OBJECTIVE: To evaluate if an automatic classification of rheumatoid arthritis (RA) metacarpophalangeal joint conditions in ultrasound images is feasible by deep learning (DL) method, to provide a more objective, automated, and fast way of RA diagnosi...

Automated Classification of Rheumatoid Arthritis, Osteoarthritis, and Normal Hand Radiographs with Deep Learning Methods.

Journal of digital imaging
Rheumatoid arthritis and hand osteoarthritis are two different arthritis that causes pain, function limitation, and permanent joint damage in the hands. Plain hand radiographs are the most commonly used imaging methods for the diagnosis, differential...

Cardiovascular disease detection using machine learning and carotid/femoral arterial imaging frameworks in rheumatoid arthritis patients.

Rheumatology international
The study proposes a novel machine learning (ML) paradigm for cardiovascular disease (CVD) detection in individuals at medium to high cardiovascular risk using data from a Greek cohort of 542 individuals with rheumatoid arthritis, or diabetes mellitu...

A deep-learning framework for metacarpal-head cartilage-thickness estimation in ultrasound rheumatological images.

Computers in biology and medicine
OBJECTIVE: Rheumatoid arthritis (RA) is a chronic disease characterized by erosive symmetrical polyarthritis. Bone and cartilage are the main joint targets of this disease. Cartilage damage is one of the most relevant determinants of physical disabil...

Association of TLR 9 gene polymorphisms with remission in patients with rheumatoid arthritis receiving TNF-α inhibitors and development of machine learning models.

Scientific reports
Toll-like receptor (TLR)-4 and TLR9 are known to play important roles in the immune system, and several studies have shown their association with the development of rheumatoid arthritis (RA) and regulation of tumor necrosis factor alpha (TNF-α). Howe...

DUBStepR is a scalable correlation-based feature selection method for accurately clustering single-cell data.

Nature communications
Feature selection (marker gene selection) is widely believed to improve clustering accuracy, and is thus a key component of single cell clustering pipelines. Existing feature selection methods perform inconsistently across datasets, occasionally even...