AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Asparagine

Showing 1 to 6 of 6 articles

Clear Filters

Near-infrared spectroscopy coupled with chemometrics algorithms for the quantitative determination of the germinability of Clostridium perfringens in four different matrices.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Clostridium perfringens (C. perfringens) has the ability to form metabolically-dormant spores that can survive food preservation processes and cause food spoilage and foodborne safety risks upon germination outgrowth. This study was conducted to inve...

[Development of an HPLC-UV Method for Free Asparagine in Grains].

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan
A novel analytical method was developed for the determination of free asparagine (Asn), which is a precursor of acrylamide, in grains. Asn was extracted from a sample with 5% (w/v) aqueous trichloroacetic acid solution, and the crude extract was clea...

Unravelling effects of flavanols and their derivatives on acrylamide formation via support vector machine modelling.

Food chemistry
This study investigated the effect of flavanols and their derivatives on acrylamide formation under low-moisture conditions via prediction using the support vector regression (SVR) approach. Acrylamide was generated in a potato-based equimolar aspara...

Protein asparagine deamidation prediction based on structures with machine learning methods.

PloS one
Chemical stability is a major concern in the development of protein therapeutics due to its impact on both efficacy and safety. Protein "hotspots" are amino acid residues that are subject to various chemical modifications, including deamidation, isom...

Amino acid composition predicts prion activity.

PLoS computational biology
Many prion-forming proteins contain glutamine/asparagine (Q/N) rich domains, and there are conflicting opinions as to the role of primary sequence in their conversion to the prion form: is this phenomenon driven primarily by amino acid composition, o...

Integrating machine learning and multi-omics analysis to develop an asparagine metabolism immunity index for improving clinical outcome and drug sensitivity in lung adenocarcinoma.

Immunologic research
Lung adenocarcinoma (LUAD) is a malignancy affecting the respiratory system. Most patients are diagnosed with advanced or metastatic lung cancer due to the fact that most of their clinical symptoms are insidious, resulting in a bleak prognosis. Given...