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Breast Neoplasms

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Radial SERS acquisition on coffee ring for Serum-based breast cancer diagnosis through Multilayer Perceptron.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The coffee-ring effect, involving spontaneous solute separation, has demonstrated promising potential in the context of patient serum analysis. In this study, an approach leveraging the coffee-ring-based analyte redistribution was developed for spect...

An appropriate DNA input for bisulfite conversion reveals LINE-1 and Alu hypermethylation in tissues and circulating cell-free DNA from cancers.

PloS one
The autonomous and active Long-Interspersed Element-1 (LINE-1, L1) and the non-autonomous Alu retrotransposon elements, contributing to 30% of the human genome, are the most abundant repeated sequences. With more than 90% of their sequences being met...

Generation of deep learning based virtual non-contrast CT using dual-layer dual-energy CT and its application to planning CT for radiotherapy.

PloS one
This paper presents a novel approach for generating virtual non-contrast planning computed tomography (VNC-pCT) images from contrast-enhanced planning CT (CE-pCT) scans using a deep learning model. Unlike previous studies, which often lacked sufficie...

Deep learning radiomics on grayscale ultrasound images assists in diagnosing benign and malignant of BI-RADS 4 lesions.

Scientific reports
This study aimed to explore a deep learning radiomics (DLR) model based on grayscale ultrasound images to assist radiologists in distinguishing between benign breast lesions (BBL) and malignant breast lesions (MBL). A total of 382 patients with breas...

BCD-TransNet: Automatic breast cancer detection and classification using transfer learning approach.

Technology and health care : official journal of the European Society for Engineering and Medicine
Breast Cancer (BC) is a predominant form of cancer diagnosed in women and one of the deadliest diseases. The important cause of death owing to the cancer amongst women is BC. However, the existing ML techniques are very challenge evaluate the perform...

Mortality Prediction in Patients With Breast Cancer by Artificial Neural Network Model and Elastic Net Regression.

Journal of research in health sciences
BACKGROUND: Breast cancer (BC) is the most common cancer in women, and it is important to identify models that can accurately predict mortality in patients with this cancer. The aim of the present study was to use the elastic net regression and artif...

A feature fusion method based on radiomic features and revised deep features for improving tumor prediction in ultrasound images.

Computers in biology and medicine
BACKGROUND: Radiomic features and deep features are both vitally helpful for the accurate prediction of tumor information in breast ultrasound. However, whether integrating radiomic features and deep features can improve the prediction performance of...

Longitudinal interpretability of deep learning based breast cancer risk prediction.

Physics in medicine and biology
Deep-learning-based models have achieved state-of-the-art breast cancer risk (BCR) prediction performance. However, these models are highly complex, and the underlying mechanisms of BCR prediction are not fully understood. Key questions include wheth...

Machine Learning to Predict the Individual Risk of Treatment-Relevant Toxicity for Patients With Breast Cancer Undergoing Neoadjuvant Systemic Treatment.

JCO clinical cancer informatics
PURPOSE: Toxicity to systemic cancer treatment represents a major anxiety for patients and a challenge to treatment plans. We aimed to develop machine learning algorithms for the upfront prediction of an individual's risk of experiencing treatment-re...